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ALMS1, Antibody

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產(chǎn)品名稱: ALMS1, Antibody
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ALMS1, Antibody


ALMS1, Antibody  的詳細(xì)介紹
Product Name

ALMS1, Antibody

Full Product Name

ALMS1 Antibody

Product Gene Name

anti-ALMS1 antibody

[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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OMIM
203800
3D Structure
ModBase 3D Structure for Q8TCU4
Other Notes
Small volumes of anti-ALMS1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Western Blot (WB) of anti-ALMS1 antibody
Western blot analysis ALMS1 using HeLa whole cell lysates
anti-ALMS1 antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for ALMS1. It may not necessarily be applicable to this product.
NCBI GI #
110349786
NCBI GeneID
7840
NCBI Accession #
NP_055935.4 [Other Products]
NCBI GenBank Nucleotide #
NM_015120.4 [Other Products]
UniProt Primary Accession #
Q8TCU4 [Other Products]
UniProt Secondary Accession #
Q53S05; Q580Q8; Q86VP9; Q9Y4G4; A0A087WZY3[Other Products]
UniProt Related Accession #
Q8TCU4[Other Products]
Molecular Weight
425,349 Da
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NCBI Official Full Name
Alstrom syndrome protein 1
NCBI Official Synonym Full Names
ALMS1, centrosome and basal body associated protein
NCBI Official Symbol
ALMS1??[Similar Products]
NCBI Official Synonym Symbols
ALSS
??[Similar Products]
NCBI Protein Information
Alstrom syndrome protein 1
UniProt Protein Name
Alstrom syndrome protein 1
Protein Family
Alstrom syndrome protein
UniProt Gene Name
ALMS1??[Similar Products]
UniProt Synonym Gene Names
KIAA0328??[Similar Products]
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NCBI Summary for ALMS1
This gene encodes a protein containing a large tandem-repeat domain as well as additional low complexity regions. The encoded protein functions in microtubule organization, particularly in the formation and maintanance of cilia. Mutations in this gene cause Alstrom syndrome. There is a pseudogene for this gene located adjacent in the same region of chromosome 2. Alternative splice variants have been described but their full length nature has not been determined. [provided by RefSeq, Apr 2014]
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UniProt Comments for ALMS1
Involved in PCM1-dependent intracellular transport. Required, directly or indirectly, for the localization of NCAPD2 to the proximal ends of centrioles. Required for proper formation and/or maintenance of primary cilia (PC), microtubule-based structures that protrude from the surface of epithelial cells.
Research Articles on ALMS1
1. T substitution in exon 16, predicting a p.Q3494* nonsense mutation, was identified in all affected subjects">Genetic study included polymerase chain reaction amplification and direct nucleotide sequencing of the entire ALMS1 gene in DNA from seven related Alstrom Syndrome patients. A homozygous single-nucleotide c.10480C>T substitution in exon 16, predicting a p.Q3494* nonsense mutation, was identified in all affected subjects
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Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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