Product Name
Dynein, Axonemal, Heavy Chain 11 (DNAH11), Antibody Pair Kit
Full Product Name
Dynein, Axonemal, Heavy Chain 11 (DNAH11) Antibody Pair Kit (with Standard)
Product Synonym Names
DNAHBL; DNAHC11; DNHBL; DPL11; Dynein,Heavy Chain Beta-Like; Axonemal beta dynein heavy chain 11; Ciliary dynein heavy chain 11
Product Gene Name
DNAH11 antibody pair kit
[Similar Products]
Matching Pairs
Antibody: Dynein, Axonemal, Heavy Chain 11 (DNAH11) (MBS2103995)
Pairing: Dynein, Axonemal, Heavy Chain 11 (DNAH11) (MBS2103995)
Comments: Matched antibody pair kit containing antibody/standard combination
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Request for Current Manual Insert
Request Current Manual
Samples
Tissue Homogenates and Other Biological Fluids
Detection Range
0.625-40ng/mL
Standard
Recombinant DNAH11 (Lyophilized, 1 vial-10ug)
Capture Antibody
Rabbit polyclonal antibody (Liquid, 1 vial-400mug/800muL)
Detection Antibody
Biotinylated Rabbit polyclonal antibody (Liquid, 1 vial-100mug/500muL)
Producte Usage
Raw materials can be used for preparation of 5x96T or 10x96T ELISA Kits.
Antibody Support Pack
Antibody Support Pack (Buffer Pack) is sold separately as catalog #MBS2090685
ISO Certification
Manufactured in an ISO 9001:2008 and ISO 13485:2003 Certified Laboratory.
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customera??s specifications, please inquire.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of DNAH11 antibody pair kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for DNAH11 antibody pair kit
Metabolic pathway
Applications Tested/Suitable for DNAH11 antibody pair kit
ELISA (EIA), Chemiluminescence Immunoassays (CLIA), ELISPOT, Luminex
NCBI/Uniprot data below describe general gene information for DNAH11. It may not necessarily be applicable to this product.
NCBI Accession #
ACN81320.1
[Other Products]
UniProt Secondary Accession #
Q9UJ82[Other Products]
UniProt Related Accession #
Q96DT5[Other Products]
Molecular Weight
520,369 Da
NCBI Official Full Name
dynein, axonemal, heavy chain 11
NCBI Official Synonym Full Names
dynein axonemal heavy chain 11
NCBI Official Symbol
DNAH11??[Similar Products]
NCBI Official Synonym Symbols
CILD7; DNHBL; DPL11; DNAHBL; DNAHC11
??[Similar Products]
NCBI Protein Information
dynein heavy chain 11, axonemal
UniProt Protein Name
Dynein heavy chain 11, axonemal
UniProt Synonym Protein Names
Axonemal beta dynein heavy chain 11; Ciliary dynein heavy chain 11
UniProt Gene Name
DNAH11??[Similar Products]
NCBI Summary for DNAH11
This gene encodes a ciliary outer dynein arm protein and is a member of the dynein heavy chain family. It is a microtubule-dependent motor ATPase and has been reported to be involved in the movement of respiratory cilia. Mutations in this gene have been implicated in causing Kartagener Syndrome (a combination of situs inversus totalis and Primary Ciliary Dyskinesia (PCD), also called Immotile Cilia Syndrome 1 (ICS1)) and male sterility. [provided by RefSeq, Mar 2013]
UniProt Comments for DNAH11
Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP.
Research Articles on DNAH11
1. Dnah11(avc)(4) did not disrupt SHF Hh signaling and caused Atrioventricular septal defects (AVSDs) only concurrently with heterotaxy, a left/right axis abnormality. In contrast, Mks1(avc)(6) disrupted SHF Hh signaling and caused AVSDs without heterotaxy.We speculate that cilia gene mutations contribute to both syndromic and non-syndromic AVSDs in humans
Precautions
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Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.