***** 1; MYH1; MYH1_HUMAN; MYH2; MYH3; MYH4; MYH6; MyHC-2x; MyHC-IIx/d; MYL1; MYL2; MYL3; MYL5; MYL6; Myosin light chain 2 regulatory cardiac slow; Myosin 1; Myosin heavy chain 1; Myosin heavy chain 1 skeletal muscle *****; Myosin heavy chain 2 skeletal muscle *****; Myosin heavy chain 2x; Myosin heavy chain 3 skeletal muscle *****; Myosin heavy chain 4 skeletal muscle *****; Myosin heavy chain 6 skeletal muscle *****; Myosin heavy chain; Myosin heavy chain IIx/d; Myosin heavy chain skeletal muscle ***** 1; Myosin II; Myosin light chain 1 alkali skeletal fast; Myosin light chain 3 alkali ventricular skeletal slow; Myosin light chain 4 alkali atrial embryonic; Myosin light chain 5 regulatory; Myosin light chain 6 alkali smooth muscle and non muscle; Myosin-1; Myosin1; skeletal muscle

For Research Use Only. Not for use in diagnostic procedures.

Polyclonal

IgG

Rabbit

MYH3 antibody detects endogenous levels of total MYH3

The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.

Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

1mg/ml (lot specific)

Store at -20 degree C. Stable for 12 months from date of receipt.

Manufactured in an ISO 9001:2015 Certified Laboratory.

Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available, please inquire.

Small volumes of anti-MYH3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Function: Muscle contraction.
Subunit Structure: Muscle myosin is a hexameric protein that consists of 2 heavy chain subunits (MHC), 2 alkali light chain subunits (MLC) and 2 regulatory light chain subunits (MLC-2).
Similarity: The rodlike tail sequence is highly repetitive, showing cycles of a 28-residue repeat pattern composed of 4 heptapeptides, characteristic for alpha-helical coiled coils.Limited proteolysis of myosin heavy chain produces 1 light meromyosin (LMM) and 1 heavy meromyosin (HMM). HMM can be further cleaved into 2 globular subfragments (S1) and 1 rod-shaped subfragment (S2). Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

Western Blot (WB), ELISA (EIA)

WB: 1:1000-3000

Western blot analysis of extracts from Hela, using MYH3 Antibody. Lane 1 was treated with the blocking peptide.

Western blot analysis of MYH3 using mouse brain lysates

Observed: 224 kDa
Predicted: 224 kDa

myosin heavy chain 3

myosin-3

Myosin-3

Myosin is a major contractile protein which converts chemical energy into mechanical energy through the hydrolysis of ATP. Myosin is a hexameric protein composed of a pair of myosin heavy chains (MYH) and two pairs of nonidentical light chains. This gene is a member of the MYH family and encodes a protein with an IQ domain and a myosin head-like domain. Mutations in this gene have been associated with two congenital contracture (arthrogryposis) syndromes, Freeman-Sheldon syndrome and Sheldon-Hall syndrome. [provided by RefSeq, Jul 2008]

Muscle contraction.CautionRepresents a conventional myosin. This protein should not be confused with the unconventional myosin-3 (MYO3).

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