Mouse Intraflagellar transport protein 122 homolog (IFT122) ELISA kit; SPG; WDR10; WDR10p; WDR140; WD repeat domain 10; intraflagellar transport 122 homolog (Chlamydomonas)

For Research Use Only. Not for use in diagnostic procedures.

Store all reagents at 2-8 degree C

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Small volumes of IFT122 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS9335087 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the intraflagellar transport 122 homolog (Chlamydomonas) (IFT122) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing IFT122. The ELISA analytical biochemical technique of the MBS9335087 kit is based on IFT122 antibody-IFT122 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect IFT122 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, IFT122. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

134,798 Da

intraflagellar transport 122

intraflagellar transport protein 122 homolog; WD repeat domain 10; WD repeat-containing protein 10; intraflagellar transport 122 homolog

Intraflagellar transport protein 122 homolog

Wdr10??[Similar Products]

IF122_MOUSE

IFT122: Required for cilia formation and Shh signaling during neuronal patterning. Defects in IFT122 are a cause of cranioectodermal dysplasia type 1 (CED1). CED1 is a disorder characterized by craniofacial, skeletal and ectodermal abnormalities. Clinical features include dolichocephaly (with or without sagittal suture synostosis), scaphocephaly, short stature, limb shortening, short ribs, narrow chest, brachydactyly, renal failure and hepatic fibrosis, small and abnormally shaped teeth, sparse hair, skin laxity and abnormal nails. 4 isoforms of the human protein are produced by alternative splicing.

Cellular Component: cytoskeleton; cell projection; membrane; cell; cytoplasm; intracellular; photoreceptor connecting cilium; cilium

Biological Process: embryonic forelimb morphogenesis; limb development; multicellular organismal development; signal transduction downstream of smoothened; embryonic body morphogenesis; camera-type eye morphogenesis; cell projection organization and biogenesis; dorsal/ventral pattern formation; negative regulation of smoothened signaling pathway; neural tube closure; cilium biogenesis; embryonic heart tube development; embryonic digit morphogenesis; negative regulation of epithelial cell proliferation; negative regulation of smoothened signaling pathway in ventral spinal cord patterning

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