Homeobox protein Hox-A3; homeobox A3; Homeo box 1E antibody; Homeo box A3 antibody; Homeobox 1E antibody; Homeobox A3 antibody; Homeobox protein HOX A3 antibody; Homeobox protein Hox-1E antibody; Homeobox protein Hox-A3 antibody; Homeobox protein HOXA3 antibody; Homeobox1E antibody; HomeoboxA3 antibody; HOX 1 antibody; Hox 1.5 like protein antibody; HOX 1E antibody; HOX A3 antibody; HOX1 antibody; Hox1.5 antibody; Hox1.5 like protein antibody; HOX1E antibody; HOXA 3 antibody; HOXA3 antibody; HXA3_HUMAN antibody; MGC10155 antibody

For Research Use Only. Not for use in diagnostic procedures.

Polyclonal

IgG

Rabbit

Immunogen affinity purified.

Lyophilized

At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.

Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Small volumes of anti-HOXA3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Description: Rabbit IgG polyclonal antibody for Homeobox protein Hox-A3(HOXA3) detection. Tested with WB, IHC-P in Human, Mouse, Rat.
Background: HOXA3(HOMEOBOX A3) is a protein that in humans is encoded by the HOXA3 gene, which is also part of the A cluster on chromosome 7. HOXA3 encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Its cytogenetic location is 7q15.2. In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. HOXA3 protein is able to complement Hoxd3 deficiency when expressed in the context of the Hoxd3 allele.

Western Blot (WB), Immunohistochemistry (IHC) Paraffin

Anti-HOXA3 antibody, MBS175402, Western blotting
All lanes: Anti HOXA3 (MBS175402) at 0.5ug/ml
WB: SW620 Whole Cell Lysate at 40ug
Predicted bind size: 46KD
Observed bind size: 46KD

Anti-HOXA3 antibody, MBS175402, IHC(P)
IHC(P): Human Pancreatic Cancer Tissue

46,369 Da

homeobox A3

homeobox protein Hox-A3; homeo box 1E; homeo box A3; Hox-1.5-like protein; homeobox protein Hox-1E

Homeobox protein Hox-A3

HOX1E??[Similar Products]

HXA3_HUMAN

In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

HOXA3: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Antp homeobox family.

Protein type: Transcription factor; DNA-binding

Chromosomal Location of Human Ortholog: 7p15.2

Cellular Component: nucleoplasm

Molecular Function: sequence-specific DNA binding; transcription factor activity

Biological Process: anterior/posterior pattern formation; specification of organ position; organ formation; regulation of transcription, DNA-dependent; transcription, DNA-dependent; thymus development; cartilage development; positive regulation of cell proliferation; glossopharyngeal nerve morphogenesis; thyroid gland development; blood vessel remodeling; angiogenesis; parathyroid gland development; embryonic skeletal morphogenesis

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