Product Name
SNAP 25, Total (Snap29), Monoclonal Antibody
Popular Item
Full Product Name
SNAP 25, Total (Synaptosomal-associated Protein 25, Synaptosomal Associated Protein 25, Synaptosomal-associated 25kD Protein, Synaptosomal-associated Protein 25kDa, SNAP25, SNAP-25, bA416N4.2, dJ1068F16.2, FLJ23079, HGNC:11132, Resistance to Inhibitors of
Product Synonym Names
Anti -SNAP 25, Total (Synaptosomal-associated Protein 25, Synaptosomal Associated Protein 25, Synaptosomal-associated 25kD Protein, Synaptosomal-associated Protein 25kDa, SNAP25, SNAP-25, bA416N4.2, dJ1068F16.2, FLJ23079, HGNC:11132, Resistance to Inhibitors of
Product Gene Name
anti-Snap29 antibody
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Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Chromosome Location
Chromosome: 16; NC_000082.6 (17406000..17430826). Location: 16 A3; 16
3D Structure
ModBase 3D Structure for Q9ERB0
Specificity
Recognizes both the intact whole form of SNAP 25 and the C. botulinum Toxin A cleaved form of SNAP 25. Has been found to bind to cleaved and uncleaved SNAP 25 aa183-197 by ELISA and cell staining techniques.
Purity/Purification
Supernatant
Supernatant
Form/Format
Supplied as a liquid. No preservative added.
Immunogen
Synthetic peptide corresponding to aa183-197 of analogue SNAP 25.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.?
Other Notes
Small volumes of anti-Snap29 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-Snap29 antibody
SNAP 25 (synaptosome-associated protein of 25kD) is a highly conserved protein anchored to the cytosolic face of membranes via palmitoyl side chains in the middle of the molecule. SNAP 25 is the target of Botulinum neurotoxin A and E which cleave off 9 and 26aas, respectively, from the C-terminus. The protein is part of the exocytotic fusion complex (v-SNARE) of neurons where it assembles with syntaxin 1 and synaptobrevin/VAMP. The protein is abundantly localized on the neuronal plasmalemma and on recycling vesicles including synaptic vesicles. It is also expressed in neuroendocrine cells.
Product Categories/Family for anti-Snap29 antibody
Antibodies; Abs to Neuroscience
Applications Tested/Suitable for anti-Snap29 antibody
ELISA (EL/EIA), Immunohistochemistry (IHC)
Application Notes for anti-Snap29 antibody
Suitable for use in ELISA and Immunohistochemistry.
Dilution: Immunohistochemistry: 1:100 stains fixed normal rat brain sections in cells known to express SNAP 25.
NCBI/Uniprot data below describe general gene information for Snap29. It may not necessarily be applicable to this product.
NCBI Accession #
NP_075837.3
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NCBI GenBank Nucleotide #
NM_023348.4
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UniProt Primary Accession #
Q9ERB0
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UniProt Secondary Accession #
Q3UGN0; Q9DBC5[Other Products]
UniProt Related Accession #
Q9ERB0[Other Products]
Molecular Weight
29,572 Da[Similar Products]
NCBI Official Full Name
synaptosomal-associated protein 29
NCBI Official Synonym Full Names
synaptosomal-associated protein 29
NCBI Official Symbol
Snap29??[Similar Products]
NCBI Official Synonym Symbols
Gs32; AI891940; AU020222; BB131856; 1300018G05Rik
??[Similar Products]
NCBI Protein Information
synaptosomal-associated protein 29; SNAP-29; golgi SNARE of 32 kDa; soluble 29 kDa NSF attachment protein; vesicle-membrane fusion protein SNAP-29
UniProt Protein Name
Synaptosomal-associated protein 29
UniProt Synonym Protein Names
Golgi SNARE of 32 kDa; Gs32; Soluble 29 kDa NSF attachment protein; Vesicle-membrane fusion protein SNAP-29
Protein Family
SNAP25 homologous protein
UniProt Gene Name
Snap29??[Similar Products]
UniProt Synonym Gene Names
SNAP-29; Gs32??[Similar Products]
UniProt Entry Name
SNP29_MOUSE
UniProt Comments for Snap29
SNAP29: Involved in multiple membrane trafficking steps. Defects in SNAP29 are the cause of CEDNIK syndrome (CEDNIK). CEDNIK is a neurocutaneous syndrome characterized by cerebral dysgenesis, neuropathy, ichthyosis and palmoplantar keratoderma. Belongs to the SNAP-25 family.
Protein type: Vesicle
Cellular Component: SNARE complex; centrosome; neuron projection; membrane; cytoplasm; plasma membrane; terminal button; synapse; cell junction
Molecular Function: SNAP receptor activity; syntaxin binding
Biological Process: synaptic vesicle fusion to presynaptic membrane; protein transport; autophagic vacuole fusion; transport; autophagy; synaptic vesicle priming
Research Articles on Snap29
1. We suggest that Rab3A may regulate SNAP-29-mediated membrane fusion during myelination.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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