ADAM-TS6; ADAMTS-6; ADAM-TS 6

For Research Use Only. Not for use in diagnostic procedures.

Polyclonal

IgG

Rabbit

Antigen affinity purification

0.5mg/mL (lot specific)

Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.

Manufactured in an ISO 9001:2015 Certified Laboratory.

Small volumes of anti-ADAMTS6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains.

Cell biology

ELISA (EIA), Immunohistochemistry (IHC)

IHC: 1:15-1:50

Immunohistochemistry of paraffin-embedded Human gasrtic cancer tissue using ADAMTS6 Polyclonal Antibody at dilution 1:15

Immunohistochemistry of paraffin-embedded Human liver cancer tissue using ADAMTS6 Polyclonal Antibody at dilution 1:15

34,189 Da

ADAM metallopeptidase with thrombospondin type 1 motif, 6

A disintegrin and metalloproteinase with thrombospondin motifs 6; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 6

A disintegrin and metalloproteinase with thrombospondin motifs 6

ADAM-TS 6; ADAM-TS6; ADAMTS-6??[Similar Products]

ATS6_HUMAN

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. [provided by RefSeq, Jul 2008]

ADAMTS6: a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. [provided by RefSeq, Jul 2008]

Protein type: Secreted; Protease; EC 3.4.24.-; Motility/polarity/chemotaxis; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 5q12

Cellular Component: proteinaceous extracellular matrix

Molecular Function: metallopeptidase activity; zinc ion binding; metalloendopeptidase activity

Biological Process: proteolysis

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