Full Product Name
ATS10 Polyclonal Antibody
Product Synonym Names
A disintegrin and metalloproteinase with thrombospondin motifs 10; ADAM-TS 10; ADAM-TS10; ADAMTS-10; EC 3.4.24.-; ADAMTS10
Product Gene Name
anti-ATS10 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q9H324
Species Reactivity
Human, Mouse
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Immunogen
Synthesized peptide derived from human protein. at AA range: 140-220
Preparation and Storage
Store at-20 degree C for 1 year.
Other Notes
Small volumes of anti-ATS10 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-ATS10 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-ATS10 antibody
WB: 1:500-2000
ELISA: 1:5000-20000
NCBI/Uniprot data below describe general gene information for ATS10. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001269281.1
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NCBI GenBank Nucleotide #
NM_001282352.1
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UniProt Primary Accession #
Q9H324
[Other Products]
UniProt Secondary Accession #
M0QZE4[Other Products]
UniProt Related Accession #
Q9H324[Other Products]
NCBI Official Full Name
A disintegrin and metalloproteinase with thrombospondin motifs 10 isoform 2
NCBI Official Synonym Full Names
ADAM metallopeptidase with thrombospondin type 1 motif 10
NCBI Official Symbol
ADAMTS10??[Similar Products]
NCBI Official Synonym Symbols
WMS; WMS1; ADAM-TS10; ADAMTS-10
??[Similar Products]
NCBI Protein Information
A disintegrin and metalloproteinase with thrombospondin motifs 10
UniProt Protein Name
A disintegrin and metalloproteinase with thrombospondin motifs 10
UniProt Gene Name
ADAMTS10??[Similar Products]
UniProt Synonym Gene Names
ADAM-TS 10; ADAM-TS10; ADAMTS-10??[Similar Products]
NCBI Summary for ATS10
This gene belongs to the ADAMTS (a disintegrin and metalloproteinase domain with thrombospondin type-1 motifs) family of zinc-dependent proteases. ADAMTS proteases are complex secreted enzymes containing a prometalloprotease domain of the reprolysin type attached to an ancillary domain with a highly conserved structure that includes at least one thrombospondin type 1 repeat. They have been demonstrated to have important roles in connective tissue organization, coagulation, inflammation, arthritis, angiogenesis and cell migration. The product of this gene plays a major role in growth and in skin, lens, and heart development. It is also a candidate gene for autosomal recessive Weill-Marchesani syndrome. [provided by RefSeq, Jul 2008]
UniProt Comments for ATS10
Metalloprotease that participate in microfibrils assembly. Microfibrils are extracellular matrix components occurring independently or along with elastin in the formation of elastic tissues.
Research Articles on ATS10
1. Using siRNA, over-expression and mutagenesis, it was found ADAMTS6 inhibits and ADAMTS10 is required for focal adhesions, epithelial cell-cell junction formation, and microfibril deposition.
Precautions
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Disclaimer
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