Product Name
Synaptosomal-associated protein (SNAP25), Monoclonal Antibody
Full Product Name
Mouse Anti Human Synaptosomal-associated protein 25
Product Synonym Names
SNAP25 Antibody; Synaptosomal-associated protein 25, Mouse Anti Human; Super-Protein; SUP; RIC4; SEC9; SNAP; RIC-4; SNAP25; SNAP-25; Synaptosomal-associated protein 25; Synaptosomal-associated 25 kDa protein; FLJ23079; bA416N4.2; dJ1068F16.2
Product Gene Name
anti-SNAP25 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Isotype
IgG1 heavy chain and kappa light chain
Purity/Purification
SNAP25 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Form/Format
1mg/ml containing PBS, pH-7.4, & 0.1% Sodium Azide.
Immunogen
Anti-human SNAP25 mAb is derived from hybridization of mouse SP2/O myeloma cells with spleen cells from BALB/c mice immunized with recombinant human SNAP25 amino acids 1-206 purified from E Coli.
Preparation and Storage
For periods up to 1 month store at 4 degree C, for longer periods of time, store at -20 degree C. Prevent freeze thaw cycles.
12 months at -20 degree C. 1 month at 4 degree C.
Other Notes
Small volumes of anti-SNAP25 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-SNAP25 antibody
Introduction: Synaptic vesicle membrane docking and fusion is mediated by SNAREs (soluble N-ethylmaleimide-sensitive factor attachment protein receptors) located on the vesicle membrane (v-SNAREs) and the target membrane (t-SNAREs). The assembled v-SNARE/t-SNARE complex consists of a bundle of four helices, one of which is supplied by v-SNARE and the other three by t-SNARE. For t-SNAREs on the plasma membrane, the protein syntaxin supplies one helix and the protein encoded by this gene contributes the other two. Therefore, SNAP25 product is a presynaptic plasma membrane protein involved in the regulation of neurotransmitter release. The synaptosomal-associated protein (SNAP-25) is an essential component of the core complex that mediates presynaptic vesicle trafficking. Thus, SNAP-25 is directly involved in the release of neurotransmitters.
Product Categories/Family for anti-SNAP25 antibody
MONOCLONAL/POLYCLONAL ANTIBODIES, MISCELLANEOUS ANTIBODIES; Monoclonal Antibodies
Applications Tested/Suitable for anti-SNAP25 antibody
ELISA (EIA), Western Blot (WB)
Application Notes for anti-SNAP25 antibody
SNAP25 antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:1,000 ~ 3,000. Recommended starting dilution is 1:2,000.
NCBI/Uniprot data below describe general gene information for SNAP25. It may not necessarily be applicable to this product.
NCBI Accession #
EDK97458.1
[Other Products]
UniProt Secondary Accession #
Q3UGN0; Q9DBC5[Other Products]
UniProt Related Accession #
Q9ERB0[Other Products]
Molecular Weight
29,572 Da
NCBI Official Full Name
synaptosomal-associated protein
NCBI Official Synonym Full Names
synaptosomal-associated protein 29
NCBI Official Symbol
Snap29??[Similar Products]
NCBI Official Synonym Symbols
Gs32; AI891940; AU020222; BB131856; 1300018G05Rik
??[Similar Products]
NCBI Protein Information
synaptosomal-associated protein 29; SNAP-29; golgi SNARE of 32 kDa; soluble 29 kDa NSF attachment protein; vesicle-membrane fusion protein SNAP-29
UniProt Protein Name
Synaptosomal-associated protein 29
UniProt Synonym Protein Names
Golgi SNARE of 32 kDa; Gs32; Soluble 29 kDa NSF attachment protein; Vesicle-membrane fusion protein SNAP-29
Protein Family
Synaptosomal-associated protein
UniProt Gene Name
Snap29??[Similar Products]
UniProt Synonym Gene Names
SNAP-29; Gs32??[Similar Products]
UniProt Entry Name
SNP29_MOUSE
UniProt Comments for SNAP25
SNAP29: Involved in multiple membrane trafficking steps. Defects in SNAP29 are the cause of CEDNIK syndrome (CEDNIK). CEDNIK is a neurocutaneous syndrome characterized by cerebral dysgenesis, neuropathy, ichthyosis and palmoplantar keratoderma. Belongs to the SNAP-25 family.
Protein type: Vesicle
Cellular Component: SNARE complex; centrosome; neuron projection; membrane; cytoplasm; plasma membrane; terminal button; synapse; cell junction
Molecular Function: SNAP receptor activity; syntaxin binding
Biological Process: synaptic vesicle fusion to presynaptic membrane; protein transport; autophagic vacuole fusion; transport; autophagy; synaptic vesicle priming
Research Articles on SNAP25
1. We suggest that Rab3A may regulate SNAP-29-mediated membrane fusion during myelination.
Precautions
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Disclaimer
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