For Research Use Only. Not for use in diagnostic procedures.

Store at 4 degree C.

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Small volumes of AS3MT elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS9136473 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Arsenic, 3-Oxidation State Methyltransferase (AS3MT) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing AS3MT. The ELISA analytical biochemical technique of the MBS9136473 kit is based on AS3MT antibody-AS3MT antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect AS3MT antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, AS3MT. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Product Overview: The ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of samples in cell culture supernatant, serum, plasma (EDTA, citrate, heparin).
Intended Use: This Human Arsenic, 3-Oxidation State Methyltransferase (AS3MT) ELISA kit is intended for laboratory research use only and not for use in diagnostic or therapeutic procedures. The stop solution changes color from blue to yellow and the intensity of the color is measured at 450 nm using a spectrophotometer. In order to measure the concentration of Human Arsenic, 3-Oxidation State Methyltransferase (AS3MT) in the sample, this Human Arsenic, 3-Oxidation State Methyltransferase (AS3MT) ELISA Kit includes a set of calibration standards. The calibration standards are assayed at the same time as the samples and allow the operator to produce a standard curve of optical density versus Human Arsenic, 3-Oxidation State Methyltransferase (AS3MT) concentration. The concentration of the samples is then determined by comparing the O.D. of the samples to the standard curve.

31,098 Da

arsenite methyltransferase

arsenite methyltransferase

Arsenite methyltransferase

CYT19??[Similar Products]

AS3MT catalyzes the transfer of a methyl group from S-adenosyl-L-methionine (AdoMet) to trivalent arsenical and may play a role in arsenic metabolism (Lin et al., 2002 [PubMed 11790780]).[supplied by OMIM, Mar 2008]

Catalyzes the transfer of a methyl group from AdoMet to trivalent arsenicals producing methylated and dimethylated arsenicals (PubMed:16407288, PubMed:25997655). It methylates arsenite to form methylarsonate, Me-AsO3H2, which is reduced by methylarsonate reductase to methylarsonite, Me-As(OH)2 (PubMed:16407288, PubMed:25997655). Methylarsonite is also a substrate and it is converted into the much less toxic compound dimethylarsinate (cacodylate), Me2As(O)-OH (PubMed:16407288, PubMed:25997655).

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