Product Name
T-Box Protein 3 (TBX3), Recombinant Protein
Full Product Name
Recombinant T-Box Protein 3 (TBX3)
Product Gene Name
TBX3 recombinant protein
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Matching Pairs
Unconjugated
Antibody: T-Box Protein 3 (TBX3) (MBS2017384)
Immunogen: T-Box Protein 3 (TBX3) (MBS2018511)
Matching Pairs
APC-CY7 Conjugated Antibody: T-Box Protein 3 (TBX3) (MBS2080558)
Immunogen: T-Box Protein 3 (TBX3) (MBS2018511)
Matching Pairs
PE Conjugated Antibody: T-Box Protein 3 (TBX3) (MBS2080559)
Immunogen: T-Box Protein 3 (TBX3) (MBS2018511)
Matching Pairs
APC Conjugated Antibody: T-Box Protein 3 (TBX3) (MBS2080560)
Immunogen: T-Box Protein 3 (TBX3) (MBS2018511)
Matching Pairs
Cy3 Conjugated Antibody: T-Box Protein 3 (TBX3) (MBS2080561)
Immunogen: T-Box Protein 3 (TBX3) (MBS2018511)
Matching Pairs
FITC Conjugated Antibody: T-Box Protein 3 (TBX3) (MBS2080562)
Immunogen: T-Box Protein 3 (TBX3) (MBS2018511)
Matching Pairs
HRP Conjugated Antibody: T-Box Protein 3 (TBX3) (MBS2080563)
Immunogen: T-Box Protein 3 (TBX3) (MBS2018511)
Matching Pairs
Biotin Conjugated Antibody: T-Box Protein 3 (TBX3) (MBS2096520)
Immunogen: T-Box Protein 3 (TBX3) (MBS2018511)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
The target protein is fused with N-terminal His-Tag, its sequence is listed below.
MGHHHHHHSG SEF- LEAK ELWDQFHKRG TEMVITKSGR RMFPPFKVRC SGLDKKAKYI LLMDIIAADD CRYKFHNSRW MVAGKADPEM PKRMYIHPDS PATGEQWMSK VVTFHKLKLT NNISDKHGFT
Chromosome Location
Chromosome: 12; NC_005111.3 (44326928..44342670, complement). Location: 12q16
3D Structure
ModBase 3D Structure for Q7TST9
Purity/Purification
> 95%
Form/Format
Supplied as lyophilized form in PBS,pH7.4, containing 5% sucrose, 0.01% sarcosyl.
Organism
Rattus norvegicus (Rat)
Expression System
Prokaryotic expression
Residues
Leu107~Thr220 (Accession # Q7TST9) with N-terminal His-Tag
Endotoxin Level
<1.0EU per 1ug (determined by the LAL method)
Reconstitution
Reconstitute in sterile PBS, pH7.2-pH7.4.
Preparation and Storage
Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.
Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test,that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. (Referring from China Biological Products Standard,which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.
ISO Certification
Manufactured in an ISO 9001:2008 and ISO 13485:2003 Certified Laboratory.
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customera??s specifications, please inquire.
Other Notes
Small volumes of TBX3 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
TBX3 recombinant protein
About the Marker: Effective Size Range: 10kDa to 70kDa.
Protein bands: 10kDa, 14kDa, 18kDa, 22kDa, 26kDa, 33kDa, 44kDa and70kDa.
Double intensity bands: The 26kDa, 18kDa, 10kDa bands are at doubleintensity to make location and size approximation of proteins of interestquick and easy.
Ready-to-use: No need to heat, dilute or add reducing agents before use.
Applications Tested/Suitable for TBX3 recombinant protein
SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP)
SDS-Page of TBX3 recombinant protein
NCBI/Uniprot data below describe general gene information for TBX3. It may not necessarily be applicable to this product.
NCBI Accession #
NP_853669.1
[Other Products]
NCBI GenBank Nucleotide #
NM_181638.1
[Other Products]
UniProt Primary Accession #
Q7TST9
[Other Products]
UniProt Related Accession #
Q7TST9[Other Products]
NCBI Official Full Name
T-box transcription factor TBX3
NCBI Official Synonym Full Names
T-box 3
NCBI Official Symbol
Tbx3??[Similar Products]
NCBI Protein Information
T-box transcription factor TBX3; T-box protein 3; T-box 3 (ulnar mammary syndrome)
UniProt Protein Name
T-box transcription factor TBX3
Protein Family
T-box transcription factor
UniProt Gene Name
Tbx3??[Similar Products]
UniProt Synonym Gene Names
T-box protein 3??[Similar Products]
UniProt Entry Name
TBX3_RAT
NCBI Summary for TBX3
human homolog acts as a transcriptional repressor and plays a role in the development of several organ systems [RGD, Feb 2006]
UniProt Comments for TBX3
TBX3: Transcriptional repressor involved in developmental processes. Probably plays a role in limb pattern formation
Protein type: DNA-binding; Transcription factor
Cellular Component: transcription factor complex; nucleus
Molecular Function: sequence-specific DNA binding; transcription factor activity
Biological Process: heart morphogenesis; embryonic forelimb morphogenesis; positive regulation of transcription, DNA-dependent; limbic system development; negative regulation of epithelial cell differentiation; palate development; negative regulation of transcription from RNA polymerase II promoter; embryonic hindlimb morphogenesis; female genitalia development; cardiac muscle cell differentiation; forelimb morphogenesis; mammary gland development; determination of anterior/posterior axis, embryo; positive regulation of cell proliferation; male genitalia development; heart looping; skeletal development; luteinizing hormone secretion; blood vessel development; specification of organ position; transcription, DNA-dependent; in utero embryonic development; stem cell maintenance; cell aging; positive regulation of cell cycle; limb morphogenesis; regulation of cell proliferation; organ morphogenesis; mesoderm morphogenesis; embryonic heart tube development; embryonic digit morphogenesis; follicle-stimulating hormone secretion; negative regulation of myoblast differentiation; negative regulation of transcription, DNA-dependent; negative regulation of apoptosis
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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