Full Product Name
FATP4 Antibody
Product Synonym Names
Solute carrier family 27 (Fatty acid transporter) member 4
Product Gene Name
anti-FATP4 antibody
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Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for G3V7V3
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Affinity purified
Form/Format
100 ug (0.5 mg/ml) affinity purified rabbit anti-FATP4 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.01% thimerosal.
Appearance: Colorless liquid
Concentration
0.5 mg/ml (lot specific)
Immunogen
Synthetic peptide surrounding amino acid 598 of rat FATP4
Positive Control
Jurkat cell lysate
Handling
The antibody solution should be gently mixed before use.
Preparation and Storage
At -20 degree C
Shelf Life: 12 months
Other Notes
Small volumes of anti-FATP4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-FATP4 antibody
Background: FATP4 is a transmembrane protein that is involved in the uptake and metabolism of long chain fatty acids. FATP4 has acyl-CoA synthase activity and contains an AMP-binding motif. FATP4 is linked to insulin resistance and metabolic disorders.
Product Categories/Family for anti-FATP4 antibody
Diabetes, Obesity & Metabolic Syndrome; Lipid Metabolism; AntibodiesAntibodies & Supporting Tools; Primary Antibodies (A-Z)
Applications Tested/Suitable for anti-FATP4 antibody
Western Blot (WB)
Application Notes for anti-FATP4 antibody
The antibody can be used for Western blot analysis (1-4 ug/ml). However, the optimal conditions should be determined individually. Blocking peptide is available separately.
Testing Data of anti-FATP4 antibody
NCBI/Uniprot data below describe general gene information for FATP4. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001094176.1
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NCBI GenBank Nucleotide #
NM_001100706.1
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UniProt Primary Accession #
G3V7V3
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Molecular Weight
72,188 Da
NCBI Official Full Name
long-chain fatty acid transport protein 4
NCBI Official Synonym Full Names
solute carrier family 27 (fatty acid transporter), member 4
NCBI Official Symbol
Slc27a4??[Similar Products]
NCBI Official Synonym Symbols
Fatp4
??[Similar Products]
NCBI Protein Information
long-chain fatty acid transport protein 4
UniProt Protein Name
Protein Slc27a4
UniProt Synonym Protein Names
Protein Slc27a4
UniProt Gene Name
Slc27a4??[Similar Products]
UniProt Entry Name
G3V7V3_RAT
UniProt Comments for FATP4
SLC27A4: Involved in translocation of long-chain fatty acids (LFCA) across the plasma membrane. Appears to be the principal fatty acid transporter in small intestinal enterocytes. Plays a role in the formation of the epidermal barrier. Required for fat absorption in early embryogenesis. Has acyl-CoA ligase activity for long-chain and very-long-chain fatty acids. Defects in SLC27A4 are the cause of ichthyosis prematurity syndrome (IPS). A keratinization disorder characterized by complications in the second trimester of pregnancy resulting from polyhydramnion, with premature birth of a child with thick caseous desquamating epidermis, respiratory complications and transient eosinophilia. After recovery during the first months of life, the symptoms are relatively benign and the patients suffer from a lifelong non-scaly ichthyosis with atopic manifestations. Belongs to the ATP-dependent AMP-binding enzyme family.
Protein type: Transporter, SLC family; Membrane protein, multi-pass; EC 6.2.1.-; Ligase; Transporter; Membrane protein, integral
Cellular Component: endoplasmic reticulum membrane; microvillus; membrane; brush border membrane; endoplasmic reticulum; integral to membrane; plasma membrane
Molecular Function: very-long-chain-fatty-acid-CoA ligase activity; long-chain-fatty-acid-CoA ligase activity
Biological Process: long-chain fatty acid transport; skin development; very-long-chain fatty acid catabolic process; very-long-chain fatty acid metabolic process; long-chain fatty acid metabolic process; fatty acid metabolic process; medium-chain fatty acid transport; response to nutrient
Research Articles on FATP4
1. FAT/CD36 and FATP4 are the most effective fatty acid transporters in skeletal muscle.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
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