Full Product Name
FATP4 Rabbit Polyclonal
Product Gene Name
anti-FATP4 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Purity/Purification
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Immunogen
Solute carrier family 27 (fatty acid transporter), member 4
Preparation and Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of anti-FATP4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-FATP4 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)
NCBI/Uniprot data below describe general gene information for FATP4. It may not necessarily be applicable to this product.
NCBI Accession #
AAC40188.1
[Other Products]
UniProt Secondary Accession #
O88562; Q3TD48[Other Products]
UniProt Related Accession #
Q91VE0[Other Products]
Molecular Weight
72,319 Da
NCBI Official Full Name
fatty acid transport protein 4, partial
NCBI Official Synonym Full Names
solute carrier family 27 (fatty acid transporter), member 4
NCBI Official Symbol
Slc27a4??[Similar Products]
NCBI Official Synonym Symbols
FATP4; BB144259
??[Similar Products]
NCBI Protein Information
long-chain fatty acid transport protein 4
UniProt Protein Name
Long-chain fatty acid transport protein 4
UniProt Synonym Protein Names
Solute carrier family 27 member 4
UniProt Gene Name
Slc27a4??[Similar Products]
UniProt Synonym Gene Names
Acsvl4; Fatp4; FATP-4; Fatty acid transport protein 4??[Similar Products]
UniProt Entry Name
S27A4_MOUSE
UniProt Comments for FATP4
SLC27A4: Involved in translocation of long-chain fatty acids (LFCA) across the plasma membrane. Appears to be the principal fatty acid transporter in small intestinal enterocytes. Plays a role in the formation of the epidermal barrier. Required for fat absorption in early embryogenesis. Has acyl-CoA ligase activity for long-chain and very-long-chain fatty acids. Defects in SLC27A4 are the cause of ichthyosis prematurity syndrome (IPS). A keratinization disorder characterized by complications in the second trimester of pregnancy resulting from polyhydramnion, with premature birth of a child with thick caseous desquamating epidermis, respiratory complications and transient eosinophilia. After recovery during the first months of life, the symptoms are relatively benign and the patients suffer from a lifelong non-scaly ichthyosis with atopic manifestations. Belongs to the ATP-dependent AMP-binding enzyme family.
Protein type: Transporter; Membrane protein, multi-pass; EC 6.2.1.-; Ligase; Membrane protein, integral; Transporter, SLC family
Cellular Component: brush border membrane; endoplasmic reticulum; endoplasmic reticulum membrane; integral to membrane; membrane; microvillus; plasma membrane
Molecular Function: 2,4-dichlorobenzoate-CoA ligase activity; 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA synthetase activity; 3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity; 3-oxo-2-(2'-pentenyl)cyclopentane-1-octanoic acid (OPC-8:0) CoA ligase activity; acyl-CoA ligase activity; aryl-CoA synthetase (ADP-forming) activity; benzoyl acetate-CoA ligase activity; branched-chain acyl-CoA synthetase (ADP-forming) activity; catalytic activity; fatty-acid ligase activity; ligase activity; long-chain-fatty-acid-CoA ligase activity; nucleotide binding; succinate-CoA ligase activity; very-long-chain-fatty-acid-CoA ligase activity
Biological Process: fatty acid metabolic process; fatty acid transport; lipid metabolic process; lipid transport; long-chain fatty acid metabolic process; long-chain fatty acid transport; medium-chain fatty acid transport; metabolic process; skin development; transport; very-long-chain fatty acid catabolic process; very-long-chain fatty acid metabolic process
Research Articles on FATP4
1. Transgenic expression of FATP1 in suprabasal keratinocytes rescued the phenotype of Fatp4 mutants, and FATP1 sorted to the same intracellular organelles as endogenous FATP4
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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