Product Name
TBX2/3, Polyclonal Antibody
Full Product Name
Anti-TBX2/3 Antibody
Product Synonym Names
TBX3; T-box transcription factor TBX3; T-box protein 3; TBX2; T-box transcription factor TBX2; T-box protein 2
Product Gene Name
anti-TBX2 antibody
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Antibody/Peptide Pairs
TBX2/3 peptide (MBS8247862) is used for blocking the activity of TBX2/3 antibody (MBS8248150)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for O15119
Species Reactivity
Human, Mouse, Rat, Bovine, Dog, Pig, Zebrafish
Specificity
Recognizes endogenous levels of TBX2/3 protein.
Purity/Purification
The antibody was purified by affinity chromatography.
Form/Format
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human TBX2/3. The exact sequence is proprietary.
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
Other Notes
Small volumes of anti-TBX2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-TBX2 antibody
Rabbit polyclonal antibody to TBX2/3
Applications Tested/Suitable for anti-TBX2 antibody
Western Blot (WB)
Application Notes for anti-TBX2 antibody
WB: 1/500 - 1/2000
Western Blot (WB) of anti-TBX2 antibody
Western blot analysis of TBX2/3 expression in A549 (A), Hela (B) whole cell lysates.
NCBI/Uniprot data below describe general gene information for TBX2. It may not necessarily be applicable to this product.
NCBI Accession #
NP_005987.3
[Other Products]
NCBI GenBank Nucleotide #
NM_005996.3
[Other Products]
UniProt Primary Accession #
O15119
[Other Products]
UniProt Secondary Accession #
Q8TB20; Q9UKF8[Other Products]
UniProt Related Accession #
O15119[Other Products]
NCBI Official Full Name
T-box transcription factor TBX3 isoform 1
NCBI Official Synonym Full Names
T-box 3
NCBI Official Symbol
TBX3??[Similar Products]
NCBI Official Synonym Symbols
UMS; XHL; TBX3-ISO
??[Similar Products]
NCBI Protein Information
T-box transcription factor TBX3
UniProt Protein Name
T-box transcription factor TBX3
Protein Family
T-box transcription factor
UniProt Gene Name
TBX3??[Similar Products]
UniProt Synonym Gene Names
T-box protein 3??[Similar Products]
UniProt Entry Name
TBX3_HUMAN
NCBI Summary for TBX2
This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This protein is a transcriptional repressor and is thought to play a role in the anterior/posterior axis of the tetrapod forelimb. Mutations in this gene cause ulnar-mammary syndrome, affecting limb, apocrine gland, tooth, hair, and genital development. Alternative splicing of this gene results in three transcript variants encoding different isoforms; however, the full length nature of one variant has not been determined. [provided by RefSeq, Jul 2008]
UniProt Comments for TBX2
Transcriptional repressor involved in developmental processes. Probably plays a role in limb pattern formation. Acts as a negative regulator of PML function in cellular senescence.
Research Articles on TBX2
1. this new molecular-grade based on the combination of TBX2 and TBX3 methylation is an excellent marker for predicting progression to muscle-invasive bladder cancer in patients with primary pTaG1/2 bladder cancer.
Precautions
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Disclaimer
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