Product Name
14-3-3 protein eta (Ywhah), Recombinant Protein
Popular Item
Full Product Name
Recombinant Rat 14-3-3 protein eta (Ywhah)
Product Gene Name
Ywhah recombinant protein
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
2-246aa, Full Length of Mature Protein
Sequence
GDREQLLQRA RLAEQAERYD DMASAMKAVT ELNEPLSNED RNLLSVAYKN VVGARRSSWR VISSIEQKTM ADGNEKKLEK VKAYREKIEK ELETVCNDVL ALLDKFLIKN CNDFQYESKV FYLKMKGDYY RYLAEVASGE KKNSVVEASE AAYKEAFEIS KEHMQPTHPI RLGLALNFSV FYYEIQNAPE QACLLAKQAF DDAIAELDTL NEDSYKDSTL IMQLLRDNLT LWTSDQQDEE AGEGN
3D Structure
ModBase 3D Structure for P68511
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of Ywhah recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
Ywhah recombinant protein
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and bovine orthologs. This gene contains a 7 bp repeat sequence in its 5 UTR, and changes in the number of this repeat have been associated with early-onset schizophrenia and psychotic bipolar disorder.
NCBI/Uniprot data below describe general gene information for Ywhah. It may not necessarily be applicable to this product.
NCBI Accession #
NP_037184.1
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NCBI GenBank Nucleotide #
NM_013052.1
[Other Products]
UniProt Primary Accession #
P68511
[Other Products]
UniProt Secondary Accession #
P11576; P70198[Other Products]
UniProt Related Accession #
P68511[Other Products]
Molecular Weight
28,212 Da
NCBI Official Full Name
14-3-3 protein eta
NCBI Official Synonym Full Names
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
NCBI Official Symbol
Ywhah??[Similar Products]
NCBI Official Synonym Symbols
14-3-3e
??[Similar Products]
NCBI Protein Information
14-3-3 protein eta
UniProt Protein Name
14-3-3 protein eta
Protein Family
14-3-3 protein
UniProt Gene Name
Ywhah??[Similar Products]
NCBI Summary for Ywhah
belongs to the 14-3-3 family of proteins; mediates signal transduction via activation of protein kinase C and calcium/calmodulin-dependent protein kinase II [RGD, Feb 2006]
UniProt Comments for Ywhah
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negatively regulates the kinase activity of PDPK1 ().
Research Articles on Ywhah
1. 14-3-3 proteins directly regulate CaMKKalpha when the enzyme is phosphorylated by protein kinase A on either Ser74 or Ser475.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
