Pr; pa; PRH1; db-s; PIF-S; pr1/Pr2; PRP-1/PRP-2

For Research Use Only. Not for use in diagnostic procedures.

Polyclonal

Rabbit

The antibody detects endogenous levels of total PRH2 protein.

Antigen affinity purification

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

0.9mg/ml (lot specific)

Store at -20 degree C

Small volumes of anti-PRH2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

PRH1 (acidic salivary proline-rich protein, HaeIII type, 1) and PRH2 (acidic salivary proline-rich protein, HaeIII type, 2), contain repeated cleavage sites for the restriction enzyme HaeIII and code for PRPs. PRH1/2, also known as salivary acidic proline-rich phosphoprotein 1/2, PRP-1/PRP-2 or parotid proline-rich protein 1/2, is a 166 amino acid secreted protein that functions as a highly potent inhibitor of calcium phosphate crystal growth. Similar to other PRPs, PRH1/2 provides a protective and reparative environment for dental enamel, which is important for teeth integrity.

Total protein Ab

Immunohistochemistry (IHC), Western Blot (WB)

Western Blot: 1:200-1000
Immunohistochemistry: 1: 20-100

Gel: 12%SDS-PAGE Lysate: 40 ug, Lane: HEPG2 cell, Primary antibody:PRH2 antibody at dilution 1/350 dilution, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes

The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PRH2 Antibody at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200)

17,016 Da

proline rich protein HaeIII subfamily 2

salivary acidic proline-rich phosphoprotein 1/2

Salivary acidic proline-rich phosphoprotein 1/2

Pa; PIF-S??[Similar Products]

PRPC_HUMAN

This gene encodes a member of the heterogeneous family of proline-rich salivary glycoproteins. The encoded preproprotein undergoes proteolytic processing to generate one or more mature isoforms before secretion from the parotid and submandibular/sublingual glands. In western population this locus is commonly biallelic and encodes proline-rich protein (PRP) isoforms, PRP-1 and PRP-2. The reference genome encodes the PRP-1 allele. Certain alleles of this gene are associated with susceptibility to dental caries. This gene is located in a cluster of closely related salivary proline-rich proteins on chromosome 12. [provided by RefSeq, Oct 2015]

PRH: PRP's act as highly potent inhibitors of crystal growth of calcium phosphates. They provide a protective and reparative environment for dental enamel which is important for the integrity of the teeth.

Protein type: Inhibitor

Chromosomal Location of Human Ortholog: 12p13.2

Cellular Component: extracellular space

Molecular Function: protein binding

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