Product Name
solute carrier family 27 (fatty acid transporter), member 4 (SLC27A4), Polyclonal Antibody
Popular Item
Full Product Name
Rabbit anti-human solute carrier family 27 (fatty acid transporter), member 4 polyclonal Antibody
Product Synonym Names
solute carrier family 27 (fatty acid transporter); member 4; SLC27A4; ACSVL4; FATP4
Product Gene Name
anti-SLC27A4 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Species Reactivity
Human, Mouse
Purity/Purification
Antigen Affinity Purified
Storage Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-5835 / sc-5834 / sc-25670
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of anti-SLC27A4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-SLC27A4 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
NCBI/Uniprot data below describe general gene information for SLC27A4. It may not necessarily be applicable to this product.
NCBI Accession #
AAH65003.1
[Other Products]
UniProt Secondary Accession #
O95186; Q96G53; A8K2F7[Other Products]
UniProt Related Accession #
Q6P1M0[Other Products]
Molecular Weight
26,001 Da[Similar Products]
NCBI Official Full Name
Solute carrier family 27 (fatty acid transporter), member 4
NCBI Official Synonym Full Names
solute carrier family 27 (fatty acid transporter), member 4
NCBI Official Symbol
SLC27A4??[Similar Products]
NCBI Official Synonym Symbols
IPS; FATP4; ACSVL4
??[Similar Products]
NCBI Protein Information
long-chain fatty acid transport protein 4
UniProt Protein Name
Long-chain fatty acid transport protein 4
UniProt Synonym Protein Names
Solute carrier family 27 member 4
Protein Family
Long-chain fatty acid transport protein
UniProt Gene Name
SLC27A4??[Similar Products]
UniProt Synonym Gene Names
ACSVL4; FATP4; FATP-4; Fatty acid transport protein 4??[Similar Products]
UniProt Entry Name
S27A4_HUMAN
NCBI Summary for SLC27A4
This gene encodes a member of a family of fatty acid transport proteins, which are involved in translocation of long-chain fatty acids cross the plasma membrane. This protein is expressed at high levels on the apical side of mature enterocytes in the small intestine, and appears to be the principal fatty acid transporter in enterocytes. Clinical studies suggest this gene as a candidate gene for the insulin resistance syndrome. Mutations in this gene have been associated with ichthyosis prematurity syndrome. [provided by RefSeq, Apr 2010]
UniProt Comments for SLC27A4
SLC27A4: Involved in translocation of long-chain fatty acids (LFCA) across the plasma membrane. Appears to be the principal fatty acid transporter in small intestinal enterocytes. Plays a role in the formation of the epidermal barrier. Required for fat absorption in early embryogenesis. Has acyl-CoA ligase activity for long-chain and very-long-chain fatty acids. Defects in SLC27A4 are the cause of ichthyosis prematurity syndrome (IPS). A keratinization disorder characterized by complications in the second trimester of pregnancy resulting from polyhydramnion, with premature birth of a child with thick caseous desquamating epidermis, respiratory complications and transient eosinophilia. After recovery during the first months of life, the symptoms are relatively benign and the patients suffer from a lifelong non-scaly ichthyosis with atopic manifestations. Belongs to the ATP-dependent AMP-binding enzyme family.
Protein type: Transporter, SLC family; Membrane protein, integral; Ligase; EC 6.2.1.-; Transporter; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 9q34.11
Cellular Component: endoplasmic reticulum membrane; microvillus; membrane; brush border membrane; plasma membrane; integral to membrane
Molecular Function: fatty acid transporter activity; nucleotide binding; very-long-chain-fatty-acid-CoA ligase activity; long-chain-fatty-acid-CoA ligase activity
Biological Process: skin development; long-chain fatty acid transport; very-long-chain fatty acid catabolic process; transport; long-chain fatty acid metabolic process; lipid metabolic process; medium-chain fatty acid transport; transmembrane transport; fatty acid transport; response to nutrient
Disease: Ichthyosis Prematurity Syndrome
Research Articles on SLC27A4
1. the cell surface protein CD36/FAT directly facilitates fatty acid transport across the plasma membrane, whereas the intracellular acyl-CoA synthetases FATP4 and ACSL1 enhance fatty acid uptake indirectly by metabolic trapping
Precautions
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