Product Name
KLK5, cDNA Clone
Popular Item
Full Product Name
KLK5 cDNA Clone
Product Gene Name
KLK5 cdna clone
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
atggctacag caagaccccc ctggatgtgg gtgctctgtg ctctgatcac agccttgctt ctgggggtca cagagcatgt tctcgccaac aatgatgttt cctgtgacca cccctctaac accgtgccct ctgggagcaa ccaggacctg ggagctgggg ccggggaaga cgcccggtcg gatgacagca gcagccgcat catcaatgga tccgactgcg atatgcacac ccagccgtgg caggccgcgc tgttgctaag gcccaaccag ctctactgcg gggcggtgtt ggtgcatcca cagtggctgc tcacggccgc ccactgcagg aagaaagttt tcagagtccg tctcggccac tactccctgt caccagttta tgaatctggg cagcagatgt tccagggggt caaatccatc ccccaccctg gctactccca ccctggccac tctaacgacc tcatgctcat caaactgaac agaagaattc gtcccactaa agatgtcaga cccatcaacg tctcctctca ttgtccctct gctgggacaa agtgcttggt gtctggctgg gggacaacca agagccccca agtgcacttc cctaaggtcc tccagtgctt gaatatcagc gtgctaagtc agaaaaggtg cgaggatgct tacccgagac agatagatga caccatgttc tgcgccggtg acaaagcagg tagagactcc tgccagggtg attctggggg gcctgtggtc tgcaatggct ccctgcaggg actcgtgtcc tggggagatt acccttgtgc ccggcccaac agaccgggtg tctacacgaa cctctgcaag ttcaccaagt ggatccagga aaccatccag gccaactcct ga
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of KLK5 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Vector Map of KLK5 cdna clone
NCBI/Uniprot data below describe general gene information for KLK5. It may not necessarily be applicable to this product.
NCBI Accession #
BC008036
[Other Products]
UniProt Secondary Accession #
Q53ZR3; Q9HBG8[Other Products]
UniProt Related Accession #
Q9Y337[Other Products]
Molecular Weight
32,019 Da
NCBI Official Full Name
Homo sapiens kallikrein-related peptidase 5, mRNA
NCBI Official Synonym Full Names
kallikrein related peptidase 5
NCBI Official Symbol
KLK5??[Similar Products]
NCBI Official Synonym Symbols
SCTE; KLKL2; KLK-L2
??[Similar Products]
NCBI Protein Information
kallikrein-5
UniProt Protein Name
Kallikrein-5
UniProt Synonym Protein Names
Kallikrein-like protein 2; KLK-L2; Stratum corneum tryptic enzyme
Protein Family
Kallikrein
UniProt Gene Name
KLK5??[Similar Products]
UniProt Synonym Gene Names
SCTE; KLK-L2??[Similar Products]
UniProt Entry Name
KLK5_HUMAN
NCBI Summary for KLK5
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its expression is up-regulated by estrogens and progestins. The encoded protein is secreted and may be involved in desquamation in the epidermis. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]
UniProt Comments for KLK5
KLK5: May be involved in desquamation. Belongs to the peptidase S1 family. Kallikrein subfamily.
Protein type: Secreted; Protease; Secreted, signal peptide; EC 3.4.21.-
Chromosomal Location of Human Ortholog: 19q13.33
Cellular Component: extracellular space
Molecular Function: peptidase activity; protein binding; serine-type endopeptidase activity; serine-type peptidase activity
Biological Process: epidermis development; positive regulation of antibacterial peptide production; positive regulation of G-protein coupled receptor protein signaling pathway
Research Articles on KLK5
1. the expression level of hK5 in tumor stromal cells is a promising biomarker for poor prognosis in TNBC.
Precautions
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Disclaimer
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