Anti -Nuclear Factor I/B (NFIB, NFIB2, NFIB3, NFI-RED)

For Research Use Only. Not for use in diagnostic procedures.

Chromosome: 9; NC_000009.11 (14081842..14398982, complement). Location: 9p24.1

Monoclonal

IgG1

8C241

Mouse

Recognizes human Nuclear Factor I/B.

Affinity Purified
Purified by Protein G affinity chromatography.

Supplied as a sterile-filtered liquid in PBS, pH 7.4, 1% BSA, 0.05% sodium azide.

May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Small volumes of anti-NFIB antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Antibodies; Abs to Transcription Factors

Western Blot (WB), Immunoprecipitation (IP)

Suitable for use in Western Blotting.
Dilution: Western Blotting: 1:1000-1:2000

47,442 Da[Similar Products]

nuclear factor I/B

nuclear factor 1 B-type; CTF; NF1-B; NFI-B; NF-I/B; OTTHUMP00000022765; OTTHUMP00000022766; OTTHUMP00000022767; OTTHUMP00000022768; OTTHUMP00000022769; nuclear factor 1/B; TGGCA-binding protein; CCAAT-box-binding transcription factor

Nuclear factor 1 B-type

NFIB_HUMAN

NFI-B: Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. Belongs to the CTF/NF-I family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 9p24.1

Cellular Component: nucleoplasm; nucleolus; nucleus

Molecular Function: DNA binding; double-stranded DNA binding

Biological Process: transcription from RNA polymerase II promoter; pontine nucleus development; glial cell differentiation; anterior commissure morphogenesis; chondrocyte differentiation; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription from RNA polymerase II promoter; DNA replication; negative regulation of DNA binding; hindbrain development

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While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

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