Product Name
ACTG1, cDNA Clone
Full Product Name
ACTG1 cDNA Clone
Product Gene Name
ACTG1 cdna clone
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
atggaagaag agatcgccgc gctggtcatt gacaatggct ccggcatgtg caaagctggt tttgctgggg acgacgctcc ccgagccgtg tttccttcca tcgtcgggcg ccccagacac cagggcgtca tggtgggcat gggccagaag gactcctacg tgggcgacga ggcccagagc aagcgtggca tcctgaccct gaagtacccc attgagcatg gcatcgtcac caactgggac gacatggaga agatctggca ccacaccttc tacaacgagc tgcgcgtggc cccggaggag cacccagtgc tgctgaccga ggcccccctg aaccccaagg ccaacagaga gaagatgact cagattatgt ttgagacctt caacaccccg gccatgtacg tggccatcca ggccgtgctg tccctctacg cctctgggcg caccactggc attgtcatgg actctggaga cggggtcacc cacacggtgc ccatctacga gggctacgcc ctcccccacg ccatcctgcg tctggacctg gctggccggg acctgaccga ctacctcatg aagatcctca ctgagcgagg ctacagcttc accaccacgg ccgagcggga aatcgtgcgc gacatcaagg agaagctgtg ctacgtcgcc ctggacttcg agcaggagat ggccaccgcc gcatcctcct cttctctgga gaagagctac gagctgcccg atggccaggt catcaccatt ggcaatgagc ggttccggtg tccggaggcg ctgttccagc cttccttcct gggtatggaa tcttgcggca tccacgagac caccttcaac tccatcatga agtgtgacgt ggacatccgc aaagacctgt acgccaacac ggtgctgtcg ggcggcacca ccatgtaccc gggcattgcc gacaggatgc agaaggagat caccgccctg gcgcccagca ccatgaagat caagatcatc gcacccccag agcgcaagta ctcggtgtgg atcggtggct ccatcctggc ctcactgtcc accttccagc agatgtggat tagcaagcag gagtacgacg agtcgggccc ctccatcgtc caccgcaaat gcttctaa
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of ACTG1 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for ACTG1. It may not necessarily be applicable to this product.
NCBI Accession #
BC000292
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UniProt Secondary Accession #
P02571; P14104; P99022; Q5U032; Q96E67; A8K7C2[Other Products]
UniProt Related Accession #
P63261[Other Products]
Molecular Weight
41,793 Da
NCBI Official Full Name
Homo sapiens actin, gamma 1, mRNA
NCBI Official Synonym Full Names
actin gamma 1
NCBI Official Symbol
ACTG1??[Similar Products]
NCBI Official Synonym Symbols
ACT; ACTG; BRWS2; DFNA20; DFNA26; HEL-176
??[Similar Products]
NCBI Protein Information
actin, cytoplasmic 2
UniProt Protein Name
Actin, cytoplasmic 2
UniProt Synonym Protein Names
Gamma-actin
UniProt Gene Name
ACTG1??[Similar Products]
UniProt Synonym Gene Names
ACTG??[Similar Products]
UniProt Entry Name
ACTG_HUMAN
NCBI Summary for ACTG1
Actins are highly conserved proteins that are involved in various types of cell motility, and maintenance of the cytoskeleton. In vertebrates, three main groups of actin isoforms, alpha, beta and gamma have been identified. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins co-exist in most cell types as components of the cytoskeleton, and as mediators of internal cell motility. Actin, gamma 1, encoded by this gene, is a cytoplasmic actin found in non-muscle cells. Mutations in this gene are associated with DFNA20/26, a subtype of autosomal dominant non-syndromic sensorineural progressive hearing loss. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jan 2011]
UniProt Comments for ACTG1
ACTG1: Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to 4 others. Belongs to the actin family.
Protein type: Motility/polarity/chemotaxis; Cytoskeletal
Chromosomal Location of Human Ortholog: 17q25
Cellular Component: cytoskeleton; cytosol; extracellular matrix; extracellular space; focal adhesion; membrane; nucleus; plasma membrane
Molecular Function: identical protein binding; protein binding; structural constituent of cytoskeleton; ubiquitin protein ligase binding
Biological Process: cell motility; ephrin receptor signaling pathway; retinal homeostasis; vascular endothelial growth factor receptor signaling pathway
Disease: Baraitser-winter Syndrome 2; Deafness, Autosomal Dominant 20
Research Articles on ACTG1
1. Three unrelated cases of rare ACTG1 variants in fetal microlissencephaly have been described.
Precautions
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Disclaimer
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