Product Name
Keratin, type II cuticular Hb1 (KRT81), Recombinant Protein
Full Product Name
Recombinant Bovine Keratin, type II cuticular Hb1 (KRT81)
Product Gene Name
KRT81 recombinant protein
[Similar Products]
Product Synonym Gene Name
KRT81[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
1-500aa, full length protein
Sequence
MTCGSGFRGR AFSCVSACGP RPGRCCITAA PYRGISCYRG LTGGFGSRSI CGGFRAGSFG RSFGYRSGGV GGLNPPCITT VSVNESLLTP LNLEIDPNAQ CVKQEEKEQI KCLNNRFAAF IDKVRFLEQQ NKLLETKLQF YQNRQCCESN LEPLFNGYIE TLRREAECVE ADSGRLSSEL NSLQEVLEGY KKKYEEEVAL RATAENEFVA LKKDVDCAYL RKSDLEANVE ALIQEIDFLR RLYEEEIRVL QAHISDTSVI VKMDNSRDLN MDNIVAEIKA QYDDIASRSR AEAESWYRSK CEEIKATVIR HGETLRRTKE EINELNRVIQ RLTAEVENAK CQNSKLEAAV TQAEQQGEAA LNDAKCKLAG LEEALQKAKQ DMACLLKEYQ EVMNSKLGLD IEIATYRRLL EGEEQRLCEG VGSVNVCVSS SRGGVVCGDL CVSGSRPVTG SVCSAPCSGN LAVSTGLCAP CGPCNSVTSC GLGGISSCGV GSCASVCRKC
3D Structure
ModBase 3D Structure for Q148H4
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of KRT81 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
KRT81 recombinant protein
This protein is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle; this hair keratin, as well as KRTHB3 and KRTHB6, is found primarily in the hair cortex. Mutations in this gene and KRTHB6 have been observed in patients with a rare dominant hair disease, monilethrix.
NCBI/Uniprot data below describe general gene information for KRT81. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001069674.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001076206.1
[Other Products]
UniProt Primary Accession #
Q148H4
[Other Products]
UniProt Related Accession #
Q148H4[Other Products]
Molecular Weight
54,613 Da
NCBI Official Full Name
keratin, type II cuticular Hb1
NCBI Official Symbol
KRT81??[Similar Products]
NCBI Protein Information
keratin, type II cuticular Hb1
UniProt Protein Name
Keratin, type II cuticular Hb1
UniProt Synonym Protein Names
Keratin-81
UniProt Gene Name
KRT81??[Similar Products]
UniProt Synonym Gene Names
K81??[Similar Products]
UniProt Comments for KRT81
MiscellaneousThere are two types of hair/microfibrillar keratin, I (acidic) and II (neutral to basic).
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
