For Research Use Only. Not for use in diagnostic procedures.

Store at 4 degree C.

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Small volumes of TRPC6 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS9137976 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Transient Receptor Potential Cation Channel Subfamily C, Member 6 (TRPC6) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing TRPC6. The ELISA analytical biochemical technique of the MBS9137976 kit is based on TRPC6 antibody-TRPC6 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect TRPC6 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, TRPC6. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Product Overview: The ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of samples in cell culture supernatant, serum, plasma (EDTA, citrate, heparin).
Intended Use: This Human Transient Receptor Potential Cation Channel Subfamily C, Member 6 (TRPC6) ELISA kit is intended for laboratory research use only and not for use in diagnostic or therapeutic procedures. The stop solution changes color from blue to yellow and the intensity of the color is measured at 450 nm using a spectrophotometer. In order to measure the concentration of Human Transient Receptor Potential Cation Channel Subfamily C, Member 6 (TRPC6) in the sample, this Human Transient Receptor Potential Cation Channel Subfamily C, Member 6 (TRPC6) ELISA Kit includes a set of calibration standards. The calibration standards are assayed at the same time as the samples and allow the operator to produce a standard curve of optical density versus Human Transient Receptor Potential Cation Channel Subfamily C, Member 6 (TRPC6) concentration. The concentration of the samples is then determined by comparing the O.D. of the samples to the standard curve.

93,187 Da

transient receptor potential cation channel subfamily C member 6

short transient receptor potential channel 6

Short transient receptor potential channel 6

TRP-6??[Similar Products]

The protein encoded by this gene forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium. Defects in this gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2). [provided by RefSeq, Mar 2009]

Thought to form a receptor-activated non-selective calcium permeant cation channel (PubMed:19936226, PubMed:23291369). Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) in a membrane-delimited fashion, independently of protein kinase C (PubMed:26892346). Seems not to be activated by intracellular calcium store depletion.

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