Product Name
Acidic mammalian chitinase (Chia), Recombinant Protein
Full Product Name
Recombinant Rat Acidic mammalian chitinase (Chia)
Product Gene Name
Chia recombinant protein
[Similar Products]
Product Synonym Gene Name
Chia[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
22-473aa, Full Length of Mature Protein
Sequence
YNLVCYFTNW AQYRPGLGSF KPDDINPCLC THLIYAFAGM QNNQITTIEW NDVTLYKAFN DLKNRNSKLK TLLAIGGWNF GTAPFTTMVS TSQNRQTFIT SVIKFLRQYG FDGLDLDWEY PGSRGSPPQD KHLFTVLVKE LREAFEQEAI ESNRPRLMVT AAVAAGISNI QAGYEIPELS QYLDFIHVMT YDLHGSWDGY TGENSPLYKL PTETGSNAYL NVDYVMNYWK DNGAPAEKLI VGFPEYGHTY ILSNPSDTGI GAPTSGNGPA GPYTRQAGFW AYYEICTFLR NGATQDWDAP QEVPYAYKGN EWVGYDNIKS FSVKAQWLKQ NNFGGAMIWA IDLDDFTGSF CDQGKFPLTS TLNKALDIPT AGCTAPDLPS EPVTTPPGSG SGGGSSGGGS EGSGFCAGKA DGLYPVADDR NAFWHCINGI TYQQHCQAGL VFDTSCNCCN WP
3D Structure
ModBase 3D Structure for Q6RY07
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of Chia recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for Chia. It may not necessarily be applicable to this product.
NCBI Accession #
NP_997469.1
[Other Products]
NCBI GenBank Nucleotide #
NM_207586.2
[Other Products]
UniProt Primary Accession #
Q6RY07
[Other Products]
UniProt Related Accession #
Q6RY07[Other Products]
Molecular Weight
51,951 Da
NCBI Official Full Name
acidic mammalian chitinase
NCBI Official Synonym Full Names
chitinase, acidic
NCBI Official Symbol
Chia??[Similar Products]
NCBI Protein Information
acidic mammalian chitinase
UniProt Protein Name
Acidic mammalian chitinase
Protein Family
Acidic mammalian chitinase
UniProt Gene Name
Chia??[Similar Products]
UniProt Synonym Gene Names
AMCase??[Similar Products]
UniProt Comments for Chia
Degrades chitin and chitotriose. May participate in the defense against nematodes, fungi and other pathogens. Plays a role in T-helper cell type 2 (Th2) immune response. Contributes to the response to IL-13 and inflammation in response to IL-13. Stimulates chemokine production by pulmonary epithelial cells. Protects lung epithelial cells against apoptosis and promotes phosphorylation of AKT1. Its function in the inflammatory response and in protecting cells against apoptosis is inhibited by allosamidin, suggesting that the function of this protein depends on carbohydrate binding ().
Research Articles on Chia
1. Invasive pulmonary aspergillosis in immunocompromised rats caused a dramatic increase in chitinase activity.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
