Product Name
A-kinase anchor protein 3 (Akap3), Recombinant Protein
Full Product Name
Recombinant Mouse A-kinase anchor protein 3 (Akap3) , partial
Product Gene Name
Akap3 recombinant protein
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for O88987
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of Akap3 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
Akap3 recombinant protein
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family, and is expressed in testis only. The encoded protein contains an RII-binding domain, and is predicted to participate in protein-protein interactions with the R-subunit of the PKA. This protein is localized to the ribs of the fibrous sheath in the principal piece of the sperm tail. It may function as a regulator of both motility- and head-associated functions such as capacitation and the acrosome reaction.
NCBI/Uniprot data below describe general gene information for Akap3. It may not necessarily be applicable to this product.
NCBI Accession #
NP_033780.2
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NCBI GenBank Nucleotide #
NM_009650.2
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UniProt Primary Accession #
O88987
[Other Products]
UniProt Secondary Accession #
Q497M9[Other Products]
UniProt Related Accession #
O88987[Other Products]
Molecular Weight
95,556 Da
NCBI Official Full Name
A-kinase anchor protein 3
NCBI Official Synonym Full Names
A kinase (PRKA) anchor protein 3
NCBI Official Symbol
Akap3??[Similar Products]
NCBI Official Synonym Symbols
Prka3
??[Similar Products]
NCBI Protein Information
A-kinase anchor protein 3
UniProt Protein Name
A-kinase anchor protein 3
UniProt Synonym Protein Names
A-kinase anchor protein 110 kDa; AKAP 110; Protein kinase A-anchoring protein 3; PRKA3
Protein Family
A-kinase anchor protein
UniProt Gene Name
Akap3??[Similar Products]
UniProt Synonym Gene Names
Akap110; AKAP-3; AKAP 110; PRKA3??[Similar Products]
UniProt Comments for Akap3
May function as a regulator of both motility- and head-associated functions such as capacitation and the acrosome reaction.
Research Articles on Akap3
1. Studied PKA subunit isoform expression in meiotic and post-meiotic mouse spermatogenic cells, and found sperm-specific AKAP3 can be found in the cytoplasm of elongating spermatids and interacts with RIalpha.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
