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LZTR1, Blocking Peptide

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產(chǎn)品名稱: LZTR1, Blocking Peptide
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簡單介紹

LZTR1, Blocking Peptide


LZTR1, Blocking Peptide  的詳細介紹
Product Name

LZTR1, Blocking Peptide

Full Product Name

LZTR1 Peptide

Product Gene Name

LZTR1 blocking peptide

[Similar Products]
Product Synonym Gene Name
LZTR-1; MGC21205; TCFL2[Similar Products]
Antibody/Peptide Pairs
LZTR1 peptide (MBS3229278) is used for blocking the activity of LZTR1 antibody (MBS3204311)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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OMIM
gene 615670
3D Structure
ModBase 3D Structure for Q8N653
Form/Format
Lyophilized powder
Preparation and Storage
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20 degree C. Avoid repeat freeze-thaw cycles.
Other Notes
Small volumes of LZTR1 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for
LZTR1 blocking peptide
This is a synthetic peptide designed for use in combination with anti-LZTR1 antibody made

Target Description: Leucine-zipper-like transcriptional regulator 1(LZTR1) is belived to be a DNA-binding protein and transcriptional regulator based on its predicted structural characteristics. The transcript is present in several essential fetal organs and is hemizygously deleted in some DiGeorge syndrome patients. LZTR1 is thought to play a critical role in embryogenesis.This gene encodes a member of the BTB-kelch superfamily. Initially described as a putative transcriptional regulator based on weak homology to members of the basic leucine zipper-like family, the encoded protein subsequently has been shown to localize exclusively to the Golgi network where it may help stabilize the Gogli complex. Deletion of this gene may be associated with DiGeorge syndrome.
Product Categories/Family for LZTR1 blocking peptide
Peptide
Applications Tested/Suitable for LZTR1 blocking peptide
Western Blot (WB)
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NCBI/Uniprot data below describe general gene information for LZTR1. It may not necessarily be applicable to this product.
NCBI GI #
47717139
NCBI GeneID
8216
NCBI Accession #
NP_006758 [Other Products]
NCBI GenBank Nucleotide #
NM_006767 [Other Products]
UniProt Primary Accession #
Q8N653 [Other Products]
UniProt Related Accession #
Q8N653[Other Products]
Molecular Weight
95kDa
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NCBI Official Full Name
leucine-zipper-like transcriptional regulator 1
NCBI Official Synonym Full Names
leucine zipper like transcription regulator 1
NCBI Official Symbol
LZTR1??[Similar Products]
NCBI Official Synonym Symbols
NS2; NS10; BTBD29; LZTR-1; SWNTS2
??[Similar Products]
NCBI Protein Information
leucine-zipper-like transcriptional regulator 1
UniProt Protein Name
Leucine-zipper-like transcriptional regulator 1
Protein Family
Leucine-zipper-like transcriptional regulator
UniProt Gene Name
LZTR1??[Similar Products]
UniProt Synonym Gene Names
TCFL2; LZTR-1??[Similar Products]
UniProt Entry Name
LZTR1_HUMAN
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NCBI Summary for LZTR1
This gene encodes a member of the BTB-kelch superfamily. Initially described as a putative transcriptional regulator based on weak homology to members of the basic leucine zipper-like family, the encoded protein subsequently has been shown to localize exclusively to the Golgi network where it may help stabilize the Gogli complex. Deletion of this gene may be associated with DiGeorge syndrome. [provided by RefSeq, Jul 2008]
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UniProt Comments for LZTR1
LZTR1: Probable transcriptional regulator that may play a crucial role in embryogenesis.

Protein type: EC 3.4.22.-; Transcription factor

Chromosomal Location of Human Ortholog: 22q11.21|22q11.1-q11.2

Molecular Function: transcription factor activity

Biological Process: anatomical structure morphogenesis; regulation of transcription, DNA-dependent

Disease: Schwannomatosis 2
Research Articles on LZTR1
1. LZTR1 mutation is associated with Noonan syndrome.
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Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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