Full Product Name
LZTR1 Polyclonal Antibody
Product Synonym Names
BTBD29; LZTR-1; SWNTS2
Product Gene Name
anti-LZTR1 antibody
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Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Affinity Purification
Immunogen
Recombinant protein of human LZTR1
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-86720 / sc-86721
Preparation and Storage
Store at -20 degree C (regular) or -80 degree C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Other Notes
Small volumes of anti-LZTR1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-LZTR1 antibody
This gene encodes a member of the BTB-kelch superfamily. Initially described as a putative transcriptional regulator based on weak homology to members of the basic leucine zipper-like family, the encoded protein subsequently has been shown to localize exclusively to the Golgi network where it may help stabilize the Gogli complex. Deletion of this gene may be associated with DiGeorge syndrome.
Applications Tested/Suitable for anti-LZTR1 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-LZTR1 antibody
WB: 1:500-1:2000, IHC: 1:50-1:200
Western Blot (WB) of anti-LZTR1 antibody
Western blot analysis of extracts of various cell lines, using LZTR1 antibody.
NCBI/Uniprot data below describe general gene information for LZTR1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_006758.2
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NCBI GenBank Nucleotide #
NM_006767.3
[Other Products]
UniProt Secondary Accession #
Q14776; Q20WK0[Other Products]
UniProt Related Accession #
Q8N653[Other Products]
Molecular Weight
Calculated MW: 95kDa
NCBI Official Full Name
leucine-zipper-like transcriptional regulator 1
NCBI Official Synonym Full Names
leucine-zipper-like transcription regulator 1
NCBI Official Symbol
LZTR1??[Similar Products]
NCBI Official Synonym Symbols
NS10; BTBD29; LZTR-1; SWNTS2
??[Similar Products]
NCBI Protein Information
leucine-zipper-like transcriptional regulator 1
UniProt Protein Name
Leucine-zipper-like transcriptional regulator 1
Protein Family
Leucine-zipper-like transcriptional regulator
UniProt Gene Name
LZTR1??[Similar Products]
UniProt Synonym Gene Names
TCFL2; LZTR-1??[Similar Products]
UniProt Entry Name
LZTR1_HUMAN
NCBI Summary for LZTR1
This gene encodes a member of the BTB-kelch superfamily. Initially described as a putative transcriptional regulator based on weak homology to members of the basic leucine zipper-like family, the encoded protein subsequently has been shown to localize exclusively to the Golgi network where it may help stabilize the Gogli complex. Deletion of this gene may be associated with DiGeorge syndrome. [provided by RefSeq, Jul 2008]
UniProt Comments for LZTR1
LZTR1: Probable transcriptional regulator that may play a crucial role in embryogenesis.
Protein type: EC 3.4.22.-; Transcription factor
Chromosomal Location of Human Ortholog: 22q11.21|22q11.1-q11.2
Cellular Component: Golgi apparatus
Molecular Function: transcription factor activity
Biological Process: anatomical structure morphogenesis; regulation of transcription, DNA-dependent
Disease: Noonan Syndrome 10; Schwannomatosis 2
Research Articles on LZTR1
1. We show for the first time that an inherited mutation in PBRM1 predisposes to RCC.
Precautions
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Disclaimer
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