Product Synonym Names
FSGS2; TRP6
Product Gene Name
anti-TRPC6 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q9Y210
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Affinity purification
Immunogen
A synthetic peptide of human TRPC6
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Preparation and Storage
Aliquot and store at-20 degree C. Avoid repeated freeze/thaw cycles.
Other Notes
Small volumes of anti-TRPC6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-TRPC6 antibody
The protein encoded by this gene forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium. Defects in this gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2).
Applications Tested/Suitable for anti-TRPC6 antibody
Western Blot (WB)
Application Notes for anti-TRPC6 antibody
WB: 1:500-1:2000
NCBI/Uniprot data below describe general gene information for TRPC6. It may not necessarily be applicable to this product.
NCBI Accession #
NP_004612.2
[Other Products]
NCBI GenBank Nucleotide #
NM_004621.5
[Other Products]
UniProt Primary Accession #
Q9Y210
[Other Products]
UniProt Secondary Accession #
Q52M59; Q9HCW3; Q9NQA8; Q9NQA9[Other Products]
UniProt Related Accession #
Q9Y210[Other Products]
NCBI Official Full Name
short transient receptor potential channel 6
NCBI Official Synonym Full Names
transient receptor potential cation channel subfamily C member 6
NCBI Official Symbol
TRPC6??[Similar Products]
NCBI Official Synonym Symbols
TRP6; FSGS2
??[Similar Products]
NCBI Protein Information
short transient receptor potential channel 6
UniProt Protein Name
Short transient receptor potential channel 6
UniProt Synonym Protein Names
Transient receptor protein 6; TRP-6
Protein Family
Short transient receptor potential channel
UniProt Gene Name
TRPC6??[Similar Products]
UniProt Synonym Gene Names
TRP-6??[Similar Products]
NCBI Summary for TRPC6
The protein encoded by this gene forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium. Defects in this gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2). [provided by RefSeq, Mar 2009]
UniProt Comments for TRPC6
Thought to form a receptor-activated non-selective calcium permeant cation channel (PubMed:19936226, PubMed:23291369). Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) in a membrane-delimited fashion, independently of protein kinase C (PubMed:26892346). Seems not to be activated by intracellular calcium store depletion.
Research Articles on TRPC6
1. axonal colocalization of TRPV4 and TRPC6 was found in the digital Meissner corpuscles
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
