Product Name
LZTR1, Blocking Peptide
Full Product Name
LZTR1 Peptide
Product Synonym Names
BTBD29; LZTR-1; SWNTS2; TCFL2; Leucine-zipper-like transcriptional regulator 1; leucine-zipper-like transcription regulator 1
Product Gene Name
LZTR1 blocking peptide
[Similar Products]
LZTR1 peptide (MBS152249) is used for blocking the activity of LZTR1 antibody (MBS151561)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q8N653
Concentration
200 ug/mL (lot specific)
Buffer
PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide
Location
14 amino acids near the amino terminus of human LZTR1.
Preparation and Storage
Store LZTR1 peptide at -20 degree C, stable for one year.
Other Notes
Small volumes of LZTR1 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for LZTR1 blocking peptide
Blocking (BL)
Application Notes for LZTR1 blocking peptide
LZTR1 pepide is used for blocking the activity of LZTR1 antibody.
NCBI/Uniprot data below describe general gene information for LZTR1. It may not necessarily be applicable to this product.
NCBI Accession #
CAJ86451
[Other Products]
UniProt Primary Accession #
Q8N653
[Other Products]
UniProt Secondary Accession #
Q14776; Q20WK0[Other Products]
UniProt Related Accession #
Q8N653[Other Products]
Molecular Weight
94,719 Da
NCBI Official Full Name
LZTR1
NCBI Official Synonym Full Names
leucine-zipper-like transcription regulator 1
NCBI Official Symbol
LZTR1??[Similar Products]
NCBI Official Synonym Symbols
BTBD29; LZTR-1; SWNTS2
??[Similar Products]
NCBI Protein Information
leucine-zipper-like transcriptional regulator 1; leucine-zipper-like regulator-1
UniProt Protein Name
Leucine-zipper-like transcriptional regulator 1
Protein Family
Leucine-zipper-like transcriptional regulator
UniProt Gene Name
LZTR1??[Similar Products]
UniProt Synonym Gene Names
TCFL2; LZTR-1??[Similar Products]
UniProt Entry Name
LZTR1_HUMAN
NCBI Summary for LZTR1
This gene encodes a member of the BTB-kelch superfamily. Initially described as a putative transcriptional regulator based on weak homology to members of the basic leucine zipper-like family, the encoded protein subsequently has been shown to localize exclusively to the Golgi network where it may help stabilize the Gogli complex. Deletion of this gene may be associated with DiGeorge syndrome. [provided by RefSeq, Jul 2008]
UniProt Comments for LZTR1
LZTR1: Probable transcriptional regulator that may play a crucial role in embryogenesis.
Protein type: EC 3.4.22.-; Transcription factor
Chromosomal Location of Human Ortholog: 22q11.21|22q11.1-q11.2
Molecular Function: transcription factor activity
Biological Process: anatomical structure morphogenesis; regulation of transcription, DNA-dependent
Disease: Schwannomatosis 2
Research Articles on LZTR1
1. Germline loss-of-function mutations in LZTR1 predispose to an inherited disorder of multiple schwannomas.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
