Full Product Name
Anti-LZTR1 Antibody
Product Synonym Names
TCFL2; Leucine-zipper-like transcriptional regulator 1; LZTR-1
Product Gene Name
anti-LZTR1 antibody
[Similar Products]
Antibody/Peptide Pairs
LZTR1 peptide (MBS823412) is used for blocking the activity of LZTR1 antibody (MBS822206)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q8N653
Species Reactivity
Human, Mouse, Rat
Specificity
Recognizes endogenous levels of LZTR1 protein.
Purity/Purification
The antibody was purified by immunogen affinity chromatography.
Form/Format
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human LZTR1. The exact sequence is proprietary.
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
Other Notes
Small volumes of anti-LZTR1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-LZTR1 antibody
Rabbit polyclonal antibody to LZTR1
Applications Tested/Suitable for anti-LZTR1 antibody
Western Blot (WB)
Application Notes for anti-LZTR1 antibody
WB (1/500 - 1/1000)
Western Blot (WB) of anti-LZTR1 antibody
Western blot analysis of LZTR1 expression in Jurkat (A), MCF7 (B), NIH3T3 (C), PC12 (D) whole cell lysates.
NCBI/Uniprot data below describe general gene information for LZTR1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_006758.2
[Other Products]
NCBI GenBank Nucleotide #
NM_006767.3
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UniProt Primary Accession #
Q8N653
[Other Products]
UniProt Secondary Accession #
Q14776; Q20WK0[Other Products]
UniProt Related Accession #
Q8N653[Other Products]
Molecular Weight
94,719 Da
NCBI Official Full Name
leucine-zipper-like transcriptional regulator 1
NCBI Official Synonym Full Names
leucine-zipper-like transcription regulator 1
NCBI Official Symbol
LZTR1??[Similar Products]
NCBI Official Synonym Symbols
BTBD29; LZTR-1; SWNTS2
??[Similar Products]
NCBI Protein Information
leucine-zipper-like transcriptional regulator 1; leucine-zipper-like regulator-1
UniProt Protein Name
Leucine-zipper-like transcriptional regulator 1
Protein Family
Leucine-zipper-like transcriptional regulator
UniProt Gene Name
LZTR1??[Similar Products]
UniProt Synonym Gene Names
TCFL2; LZTR-1??[Similar Products]
UniProt Entry Name
LZTR1_HUMAN
NCBI Summary for LZTR1
This gene encodes a member of the BTB-kelch superfamily. Initially described as a putative transcriptional regulator based on weak homology to members of the basic leucine zipper-like family, the encoded protein subsequently has been shown to localize exclusively to the Golgi network where it may help stabilize the Gogli complex. Deletion of this gene may be associated with DiGeorge syndrome. [provided by RefSeq, Jul 2008]
UniProt Comments for LZTR1
LZTR1: Probable transcriptional regulator that may play a crucial role in embryogenesis.
Protein type: EC 3.4.22.-; Transcription factor
Chromosomal Location of Human Ortholog: 22q11.21|22q11.1-q11.2
Molecular Function: transcription factor activity
Biological Process: anatomical structure morphogenesis; regulation of transcription, DNA-dependent
Disease: Schwannomatosis 2
Research Articles on LZTR1
1. Germline loss-of-function mutations in LZTR1 predispose to an inherited disorder of multiple schwannomas.
Precautions
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Disclaimer
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