Goat Polyclonal to Human PRODH; PRODH; HSPOX2; p53-induced gene 6 protein; POX; POX2; Proline oxidase; mitochondrial; Proline dehydrogenase; Proline oxidase; Proline oxidase 2; SCZD4; TP53I6; PRODH1; PIG6

For Research Use Only. Not for use in diagnostic procedures.

Polyclonal

IgG

Rabbit

Human PRODH

Affinity Purified

PBS with 0.02% sodium azide, 50% glycerol, pH 7.3

Store at -20 degree C.
Avoid freeze-thaw cycles.

Small volumes of anti-PRODH antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

PRODH is a mitochondrial protein that catalyzes the first step inproline degradation. Mutations in this gene are associated withhyperprolinemia type 1 and susceptibility to schizophrenia 4 (SCZD4). This gene is located on chromosome 22q11.21, a region which has alsobeen associated with the contiguous gene deletion syndromes, DiGeorge and CATCH22. Alternatively spliced transcript variants encodingdifferent isoforms have been found for this gene.

Immunohistochemistry (IHC), Immunohistochemistry (IHC) Paraffin, Western Blot (WB)

IHC: 1:50-1:200
IHC-P: 1:100
WB: 1:500-1:2000

Human Skeletal Muscle: Formalin-Fixed, Paraffin-Embedded (FFPE)

Western blot analysis of extracts of various cell lines.

Western blot analysis of extracts of various cell lines, using PRODH antibody.

59,231 Da

proline dehydrogenase 1

proline dehydrogenase 1, mitochondrial

Proline dehydrogenase 1, mitochondrial

This gene encodes a mitochondrial protein that catalyzes the first step in proline degradation. Mutations in this gene are associated with hyperprolinemia type 1 and susceptibility to schizophrenia 4 (SCZD4). This gene is located on chromosome 22q11.21, a region which has also been associated with the contiguous gene deletion syndromes, DiGeorge and CATCH22. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2010]

Converts proline to delta-1-pyrroline-5-carboxylate.

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