Full Product Name
MYOT antibody - C-terminal region
Product Gene Name
anti-MYOT antibody
[Similar Products]
Product Synonym Gene Name
LGMD1; LGMD1A; TTID[Similar Products]
Antibody/Peptide Pairs
MYOT peptide (MBS3241200) is used for blocking the activity of MYOT antibody (MBS3216299)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence
Synthetic peptide located within the following region: RNNEMVQFNT DRISLYQDNT GRVTLLIKDV NKKDAGWYTV SAVNEAGVTT
3D Structure
ModBase 3D Structure for Q9UBF9
Species Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Purity/Purification
Affinity Purified
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Other Notes
Small volumes of anti-MYOT antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-MYOT antibody
This is a rabbit polyclonal antibody against MYOT. It was validated on Western Blot
Target Description: This gene encodes a cystoskeletal protein which plays a significant role in the stability of thin filaments during muscle contraction. This protein binds F-actin, crosslinks actin filaments, and prevents latrunculin A-induced filament disassembly. Mutations in this gene have been associated with limb-girdle muscular dystrophy and myofibrillar myopathies. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
Product Categories/Family for anti-MYOT antibody
Polyclonal; Transcription Factor; Transcription Regulation; Cell Biology; Developmental Biology; Epigenetics; DNA/RNA/Protein Interactions; Meiosis/Mitosis/Cell Cycle;
Applications Tested/Suitable for anti-MYOT antibody
Western Blot (WB)
Western Blot (WB) of anti-MYOT antibody
WB Suggested Anti-MYOT Antibody
Titration: 1.0 ug/ml
Positive Control: Fetal Liver
NCBI/Uniprot data below describe general gene information for MYOT. It may not necessarily be applicable to this product.
NCBI Accession #
NP_006781
[Other Products]
NCBI GenBank Nucleotide #
NM_006790
[Other Products]
UniProt Primary Accession #
Q9UBF9
[Other Products]
UniProt Related Accession #
Q9UBF9[Other Products]
NCBI Official Full Name
myotilin isoform a
NCBI Official Synonym Full Names
myotilin
NCBI Official Symbol
MYOT??[Similar Products]
NCBI Official Synonym Symbols
MFM3; TTID; TTOD; LGMD1; LGMD1A
??[Similar Products]
NCBI Protein Information
myotilin
UniProt Protein Name
Myotilin
UniProt Synonym Protein Names
57 kDa cytoskeletal protein; Myofibrillar titin-like Ig domains protein; Titin immunoglobulin domain protein
UniProt Gene Name
MYOT??[Similar Products]
UniProt Synonym Gene Names
TTID??[Similar Products]
UniProt Entry Name
MYOTI_HUMAN
NCBI Summary for MYOT
This gene encodes a cystoskeletal protein which plays a significant role in the stability of thin filaments during muscle contraction. This protein binds F-actin, crosslinks actin filaments, and prevents latrunculin A-induced filament disassembly. Mutations in this gene have been associated with limb-girdle muscular dystrophy and myofibrillar myopathies. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.[provided by RefSeq, Oct 2008]
Research Articles on MYOT
1. sequence conservation analysis of myotilin shed light on the molecular basis of myotilinopathies and revealed several motifs in Ig domains found also in I-band proteins.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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