Product Name
LZTR1, Polyclonal Antibody
Popular Item
Product Gene Name
anti-LZTR1 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q8N653
Species Reactivity
Human, Mouse, Rat
Immunogen
Recombinant Protein
Other Notes
Small volumes of anti-LZTR1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for anti-LZTR1 antibody
Polyclonal
Applications Tested/Suitable for anti-LZTR1 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Western Blot (WB) of anti-LZTR1 antibody
Western blot analysis of extracts of various cell lines, using LZTR1 antibody at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Enhanced Kit.
Exposure time: 90s.
Immunohistochemistry (IHC) of anti-LZTR1 antibody
Immunohistochemistry of paraffin-embedded human kidney using LZTR1 antibody at dilution of 1:100 (40x lens).
NCBI/Uniprot data below describe general gene information for LZTR1. It may not necessarily be applicable to this product.
NCBI Accession #
Q8N653.2
[Other Products]
UniProt Primary Accession #
Q8N653
[Other Products]
UniProt Secondary Accession #
Q14776; Q20WK0[Other Products]
UniProt Related Accession #
Q8N653[Other Products]
NCBI Official Full Name
Leucine-zipper-like transcriptional regulator 1
NCBI Official Synonym Full Names
leucine-zipper-like transcription regulator 1
NCBI Official Symbol
LZTR1??[Similar Products]
NCBI Official Synonym Symbols
BTBD29; LZTR-1; SWNTS2
??[Similar Products]
NCBI Protein Information
leucine-zipper-like transcriptional regulator 1; leucine-zipper-like regulator-1
UniProt Protein Name
Leucine-zipper-like transcriptional regulator 1
Protein Family
Leucine-zipper-like transcriptional regulator
UniProt Gene Name
LZTR1??[Similar Products]
UniProt Synonym Gene Names
TCFL2; LZTR-1??[Similar Products]
UniProt Entry Name
LZTR1_HUMAN
NCBI Summary for LZTR1
This gene encodes a member of the BTB-kelch superfamily. Initially described as a putative transcriptional regulator based on weak homology to members of the basic leucine zipper-like family, the encoded protein subsequently has been shown to localize exclusively to the Golgi network where it may help stabilize the Gogli complex. Deletion of this gene may be associated with DiGeorge syndrome. [provided by RefSeq, Jul 2008]
UniProt Comments for LZTR1
LZTR1: Probable transcriptional regulator that may play a crucial role in embryogenesis.
Protein type: Transcription factor; EC 3.4.22.-
Chromosomal Location of Human Ortholog: 22q11.21|22q11.1-q11.2
Molecular Function: transcription factor activity
Biological Process: anatomical structure morphogenesis; regulation of transcription, DNA-dependent
Disease: Schwannomatosis 2
Research Articles on LZTR1
1. Germline loss-of-function mutations in LZTR1 predispose to an inherited disorder of multiple schwannomas.
Precautions
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Disclaimer
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