Full Product Name
SOX3 Polyclonal Antibody
Product Synonym Names
Transcription factor SOX-3; SOX3
Product Gene Name
anti-SOX3 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P41225
Species Reactivity
Human, Mouse
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Preparation and Storage
Store at-20 degree C for 1 year.
Other Notes
Small volumes of anti-SOX3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-SOX3 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-SOX3 antibody
WB: 1:500-2000
ELISA: 1:5000-20000
NCBI/Uniprot data below describe general gene information for SOX3. It may not necessarily be applicable to this product.
NCBI Accession #
NP_005625.2
[Other Products]
NCBI GenBank Nucleotide #
NM_005634.2
[Other Products]
UniProt Primary Accession #
P41225
[Other Products]
UniProt Secondary Accession #
P35714; Q5JWI3; Q9NP49[Other Products]
UniProt Related Accession #
P41225[Other Products]
NCBI Official Full Name
transcription factor SOX-3
NCBI Official Synonym Full Names
SRY-box 3
NCBI Official Symbol
SOX3??[Similar Products]
NCBI Official Synonym Symbols
PHP; GHDX; MRGH; PHPX; SOXB
??[Similar Products]
NCBI Protein Information
transcription factor SOX-3
UniProt Protein Name
Transcription factor SOX-3
Protein Family
Transcription factor
UniProt Gene Name
SOX3??[Similar Products]
NCBI Summary for SOX3
This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. Mutations in this gene have been associated with X-linked cognitive disability with growth hormone deficiency. [provided by RefSeq, Jul 2008]
UniProt Comments for SOX3
Transcription factor required during the formation of the hypothalamo-pituitary axis. May function as a switch in neuronal development. Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation. Required also within the pharyngeal epithelia for craniofacial morphogenesis. Controls a genetic switch in male development. Is necessary for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granulosa cells ().
Research Articles on SOX3
1. deletion of the SOX3 gene may have a role in intellectual disability with hemophilia B
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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