Prostaglandin G/H synthase 1; Cyclooxygenase-1; COX-1; Prostaglandin H2 synthase 1; PGH synthase 1; PGHS-1; PHS 1; Prostaglandin-endoperoxide synthase 1; PTGS1; COX1

For Research Use Only. Not for use in diagnostic procedures.

One 96-Well Plate

Store at 4 degree C.

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Small volumes of Cox1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS9500143 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Cox1, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing Cox1. The ELISA analytical biochemical technique of the MBS9500143 kit is based on Cox1 antibody-Cox1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect Cox1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, Cox1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Cell Based ELISA Kit

68656; 64513

prostaglandin-endoperoxide synthase 1

prostaglandin G/H synthase 1

Prostaglandin G/H synthase 1

COX1; COX-1; PGH synthase 1; PGHS-1; PHS 1??[Similar Products]

This is one of two genes encoding similar enzymes that catalyze the conversion of arachinodate to prostaglandin. The encoded protein regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. Based on its ability to function as both a cyclooxygenase and as a peroxidase, the encoded protein has been identified as a moonlighting protein. The protein may promote cell proliferation during tumor progression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]

COX-1: May play an important role in regulating or promoting cell proliferation in some normal and neoplastically transformed cells. Homodimer. Belongs to the prostaglandin G/H synthase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 1.14.99.1; Lipid Metabolism - arachidonic acid; Oxidoreductase

Chromosomal Location of Human Ortholog: 9q33.2

Cellular Component: cytoplasm; endoplasmic reticulum membrane; Golgi apparatus; intracellular membrane-bound organelle; nucleus; photoreceptor outer segment

Molecular Function: dioxygenase activity; heme binding; metal ion binding; peroxidase activity; prostaglandin-endoperoxide synthase activity

Biological Process: cyclooxygenase pathway; inflammatory response; lipid metabolic process; prostaglandin biosynthetic process; regulation of blood pressure; regulation of cell proliferation; response to oxidative stress; xenobiotic metabolic process

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