Full Product Name
USP26 Antibody
Product Gene Name
anti-USP26 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q9BXU7
Other Notes
Small volumes of anti-USP26 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Western Blot (WB) of anti-USP26 antibody
Western blot analysis USP26 using HuvEc whole cell lysates
NCBI/Uniprot data below describe general gene information for USP26. It may not necessarily be applicable to this product.
NCBI Accession #
NP_114113.1
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NCBI GenBank Nucleotide #
NM_031907.1
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UniProt Primary Accession #
Q9BXU7
[Other Products]
UniProt Secondary Accession #
Q5H9H4; B9WRT6[Other Products]
UniProt Related Accession #
Q9BXU7[Other Products]
Molecular Weight
104,047 Da
NCBI Official Full Name
ubiquitin carboxyl-terminal hydrolase 26
NCBI Official Synonym Full Names
ubiquitin specific peptidase 26
NCBI Official Symbol
USP26??[Similar Products]
NCBI Protein Information
ubiquitin carboxyl-terminal hydrolase 26
UniProt Protein Name
Ubiquitin carboxyl-terminal hydrolase 26
UniProt Synonym Protein Names
Deubiquitinating enzyme 26; Ubiquitin thioesterase 26; Ubiquitin-specific-processing protease 26
UniProt Gene Name
USP26??[Similar Products]
NCBI Summary for USP26
This gene encodes a member of the ubiquitin-specific processing (UBP) family of proteases and is a deubiquitinating enzyme (DUB) with His and Cys domains. It is specifically expressed in testis tissue. Mutations in this gene have been associated with Sertoli cell-only syndrome and male infertility. [provided by RefSeq, Jul 2008]
UniProt Comments for USP26
Involved in the ubiquitin-dependent proteolytic pathway in conjunction with the 26S proteasome (). Deubiquitinates the androgen receptor and regulates the androgen receptor signaling pathway.
Research Articles on USP26
1. findings demonstrate TGF-beta enhances expression of USP26 and reinforces SMAD7 stability by limiting the ubiquitin-mediated turnover of SMAD7; clinically, loss of USP26 correlates with high TGF-beta activity and confers poor prognosis in glioblastoma; data identify USP26 as a novel negative regulator of the TGF-beta pathway and suggest that loss of USP26 expression may be an important factor in glioblastoma pathogenesis
Precautions
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Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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