PTGS1; COX1; COX3; PHS1; PCOX1; PGHS1; PTGHS; PGG/HS; PGHS-1; prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase); prostaglandin G/H synthase and cyclooxygenase; RP11-542K23. 6; COX1 / PTGS1

For Research Use Only. Not for use in diagnostic procedures.

100ug of dried peptide

Shipped at ambient temperature, store at -20 degree C

Manufactured in an ISO 9001:2008 Certified Laboratory.

Small volumes of PTGS1 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

72,010 Da

prostaglandin-endoperoxide synthase 1

prostaglandin G/H synthase 1

Prostaglandin G/H synthase 1

COX1; COX-1; PGH synthase 1; PGHS-1; PHS 1??[Similar Products]

PGH1_HUMAN

This is one of two genes encoding similar enzymes that catalyze the conversion of arachinodate to prostaglandin. The encoded protein regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. Based on its ability to function as both a cyclooxygenase and as a peroxidase, the encoded protein has been identified as a moonlighting protein. The protein may promote cell proliferation during tumor progression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]

COX-1: May play an important role in regulating or promoting cell proliferation in some normal and neoplastically transformed cells. Homodimer. Belongs to the prostaglandin G/H synthase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Oxidoreductase; Lipid Metabolism - arachidonic acid; EC 1.14.99.1

Chromosomal Location of Human Ortholog: 9q32-q33.3

Cellular Component: cytoplasm; endoplasmic reticulum membrane; Golgi apparatus; intracellular membrane-bound organelle; nuclear envelope; nucleus; photoreceptor outer segment

Molecular Function: dioxygenase activity; heme binding; lipid binding; metal ion binding; peroxidase activity; prostaglandin-endoperoxide synthase activity

Biological Process: aging; cyclooxygenase pathway; inflammatory response; learning; lipid metabolic process; memory; negative regulation of epinephrine secretion; positive regulation of smooth muscle contraction; positive regulation of vasoconstriction; prostaglandin biosynthetic process; regulation of blood pressure; regulation of cell proliferation; response to corticosterone stimulus; response to organic nitrogen; response to oxidative stress; sensory perception of pain; xenobiotic metabolic process

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