Full Product Name
QDPR Antibody (Rabbit Polyclonal)
Product Gene Name
anti-QDPR antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Species Reactivity
Human
Predicted: Rat, Mouse
Form/Format
Purified by protein affinity column containing 1% BSA and 0.02% NaN3
Preparation and Storage
Already reconstituted in 200ul sterile H2O. The antibody is stable for at least one year when stored at-20 degree C after reconstitution. Avoid repeated freeze/defrost cycles.
Other Notes
Small volumes of anti-QDPR antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-QDPR antibody
Rabbit polyclonal QDPR (1) antibody was raised against a recombinate human QDPR protein 35-240aa (BC000576).
Applications Tested/Suitable for anti-QDPR antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-QDPR antibody
ELISA: 1:20,000-1:80,000
WB: 1:200-1:1,000
IHC: 1:100-1:500
NCBI/Uniprot data below describe general gene information for QDPR. It may not necessarily be applicable to this product.
NCBI Accession #
BC000576
[Other Products]
UniProt Secondary Accession #
Q53F52; Q9H3M5; A8K158; B3KW71[Other Products]
UniProt Related Accession #
P09417[Other Products]
Molecular Weight
22,408 Da
NCBI Official Full Name
Homo sapiens quinoid dihydropteridine reductase, mRNA
NCBI Official Synonym Full Names
quinoid dihydropteridine reductase
NCBI Official Symbol
QDPR??[Similar Products]
NCBI Official Synonym Symbols
DHPR; PKU2; SDR33C1
??[Similar Products]
NCBI Protein Information
dihydropteridine reductase
UniProt Protein Name
Dihydropteridine reductase
UniProt Synonym Protein Names
HDHPR; Quinoid dihydropteridine reductase; Short chain dehydrogenase/reductase family 33C member 1
Protein Family
Dihydropteridine reductase
UniProt Gene Name
QDPR??[Similar Products]
UniProt Synonym Gene Names
DHPR; SDR33C1??[Similar Products]
NCBI Summary for QDPR
This gene encodes the enzyme dihydropteridine reductase, which catalyzes the NADH-mediated reduction of quinonoid dihydrobiopterin. This enzyme is an essential component of the pterin-dependent aromatic amino acid hydroxylating systems. Mutations in this gene resulting in QDPR deficiency include aberrant splicing, amino acid substitutions, insertions, or premature terminations. Dihydropteridine reductase deficiency presents as atypical phenylketonuria due to insufficient production of biopterin, a cofactor for phenylalanine hydroxylase. [provided by RefSeq, Jul 2008]
UniProt Comments for QDPR
The product of this enzyme, tetrahydrobiopterin (BH-4), is an essential cofactor for phenylalanine, tyrosine, and tryptophan hydroxylases.
Research Articles on QDPR
1. Mutation of dihydropteridine reductase (QDPR) inhibited the regulation of TOR serine-threonine kinases (mTOR), suggesting that QDPR is a positive regulator of autophagy via suppressing mTOR signaling.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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