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Aquaporin 9, Polyclonal Antibody

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產(chǎn)品名稱: Aquaporin 9, Polyclonal Antibody
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Aquaporin 9, Polyclonal Antibody


Aquaporin 9, Polyclonal Antibody  的詳細(xì)介紹
Product Name

Aquaporin 9 (AQP9), Polyclonal Antibody

Popular Item
Full Product Name

Anti-Aquaporin 9 antibody

Product Synonym Names
Aquaporin-9; aquaporin 9; AQP 9 antibody; AQP-9 antibody; AQP9 antibody; AQP9_HUMAN antibody; Aquaglyceroporin-9 antibody; Aquaporin-9 antibody; Aquaporin9 antibody; HsT 17287 antibody; HsT17287 antibody; Small solute channel 1 antibody; SSC 1 antibody; SSC1 antibody
Product Gene Name

anti-AQP9 antibody

[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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3D Structure
ModBase 3D Structure for Q9JJJ3
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Mouse
Purity/Purification
Immunogen affinity purified.
Form/Format
Lyophilized
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of mouse Aquaporin 9 (263-278aa VLFIQMHHSNPDPEVK).
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Preparation and Storage
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of anti-AQP9 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for
anti-AQP9 antibody
Description: Rabbit IgG polyclonal antibody for Aquaporin-9(AQP9) detection. Tested with WB in Mouse.
Background: Aquaporin-9 is a protein that in humans is encoded by the AQP9 gene. AQP9 encodes a 295-amino-acid protein with the amino acid sequence identity with AQP3(48%), AQP7(45%), and other aquaporins(approximately 30%), suggesting that AQP3, AQP7, and AQP9 belong to a subfamily of the aquaporin family. AQP9 is the major glycerol channel in mouse erythrocytes and suggest that this transport pathway may contribute to the virulence of intraerythrocytic stages of malarial infection.
Applications Tested/Suitable for anti-AQP9 antibody
Western Blot (WB)
Application Notes for anti-AQP9 antibody
Western Blot (WB)

Concentration: 0.1-0.5ug/ml
Tested Species: Ms
Predicted Species: n/a
Antigen Retrieval: n/a

Tested Species: In-house tested species with positive reults.
Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested.
Optimal dilutions should be determined by end users.

Western Blot (WB) of anti-AQP9 antibody
Anti-Aquaporin 9 antibody, MBS176240, Western blotting
All lanes: Anti Aquaporin 9 (MBS176240) at 0.5ug/ml
Lane 1: Mouse Liver Tissue Lysate at 50ug
Lane 2: Mouse Lung Tissue Lysate at 50ug
Lane 3: Mouse Spleen Tissue Lysate at 50ug
Lane 4: Mouse Testis Tissue Lysate at 50ug
Lane 5: PC-12 Whole Cell Lysate at 40ug
Predicted bind size: 31KD
Observed bind size: 31KD
anti-AQP9 antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for AQP9. It may not necessarily be applicable to this product.
NCBI GI #
47116925
NCBI GeneID
64008
NCBI Accession #
Q9JJJ3.1 [Other Products]
UniProt Primary Accession #
Q9JJJ3 [Other Products]
UniProt Related Accession #
Q9JJJ3[Other Products]
Molecular Weight
31,764 Da
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NCBI Official Full Name
Aquaporin-9
NCBI Official Synonym Full Names
aquaporin 9
NCBI Official Symbol
Aqp9??[Similar Products]
NCBI Official Synonym Symbols
AQP-9; AI266899; 1700020I22Rik
??[Similar Products]
NCBI Protein Information
aquaporin-9; aquaglyceroporin-9
UniProt Protein Name
Aquaporin-9
UniProt Synonym Protein Names
Aquaglyceroporin-9
Protein Family
Aquaporin
UniProt Gene Name
Aqp9??[Similar Products]
UniProt Synonym Gene Names
AQP-9??[Similar Products]
UniProt Entry Name
AQP9_MOUSE
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NCBI Summary for AQP9
This gene encodes a member of the aquaglyceroporin subfamily of aquaporins. This protein transports water, glycerol, urea, purines and pyrimidines and plays a role in glycerol metabolism and osteoclast differentiation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012]
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UniProt Comments for AQP9
AQP9: Forms a channel with a broad specificity. Mediates passage of a wide variety of non-charged solutes including carbamides, polyols, purines, and pyrimidines in a phloretin- and mercury-sensitive manner, whereas amino acids, cyclic sugars, Na(+), K(+), Cl(-), and deprotonated monocarboxylates are excluded. Also permeable to urea and glycerol. Belongs to the MIP/aquaporin (TC 1.A.8) family.

Protein type: Membrane protein, integral; Channel, misc.; Transporter, aquaporin family; Membrane protein, multi-pass; Transporter

Cellular Component: membrane; intracellular membrane-bound organelle; cell; integral to plasma membrane; basolateral plasma membrane; integral to membrane

Molecular Function: purine transmembrane transporter activity; pyrimidine transmembrane transporter activity; transporter activity; urea transmembrane transporter activity; water channel activity; glycerol channel activity

Biological Process: polyol transport; glycerol transport; cellular water homeostasis; nucleobase, nucleoside, nucleotide and nucleic acid transport; amine transport; cellular response to stress; water transport; purine transport; response to organic substance; response to mercury ion; transport; pyrimidine transport; canalicular bile acid transport; transmembrane transport
Research Articles on AQP9
1. Results suggest implication of AQP9 in liver steatosis. The reduction of hepatocyte AQP9 and, consequently, glycerol permeability might be a defensive mechanism to counteract further fat infiltration in liver parenchyma.
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Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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