Product Name
Aquaporin-9 (Aqp9), Recombinant Protein
Full Product Name
Recombinant Mouse Aquaporin-9 (Aqp9)
Product Gene Name
Aqp9 recombinant protein
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Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
1-295aa; full length protein
Sequence
MPSEKDRAKK NLVQRLALKS CLAKETLSEF LGTFIMIVLG CGSIAQAVLS REKAGGIITI NIGFATAVVM ALYATFGVSG GHINPAVSFA MCTFGRMEWF KFPFYVGAQL LGAFVGAATV FGIYYDGLMA FADGKLLITG ENGTAFIFAT YPKPFVSVPG AFVDQVVSTM FLLLIVFAIF DSRNLGVPRG LEPIVIGLLI IVISCSLGLN SGCAMNPARD LSPRLFTALA GWGFEVFTFG NNFWWIPVVG PMIGAVLGGL IYVLFIQMHH SNPDPEVKAE PAENNLEKHE LSVIM
3D Structure
ModBase 3D Structure for Q9JJJ3
Host
Cell Free Expression
Form/Format
Liquid containing glycerol
Storage Buffer
Tris-based buffer, 50% glycerol.
Preparation and Storage
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of Aqp9 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for Aqp9 recombinant protein
Transmembrane Protein
Application Notes for Aqp9 recombinant protein
This is a recombinant transmembrane protein expressed in a cell-free expression system.
NCBI/Uniprot data below describe general gene information for Aqp9. It may not necessarily be applicable to this product.
NCBI Accession #
NP_071309.1
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NCBI GenBank Nucleotide #
NM_022026.3
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UniProt Primary Accession #
Q9JJJ3
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UniProt Related Accession #
Q9JJJ3[Other Products]
Molecular Weight
31,764 Da
NCBI Official Full Name
aquaporin-9 isoform 1
NCBI Official Synonym Full Names
aquaporin 9
NCBI Official Symbol
Aqp9??[Similar Products]
NCBI Official Synonym Symbols
AQP-9; AI266899; 1700020I22Rik
??[Similar Products]
NCBI Protein Information
aquaporin-9
UniProt Protein Name
Aquaporin-9
UniProt Synonym Protein Names
Aquaglyceroporin-9
UniProt Gene Name
Aqp9??[Similar Products]
UniProt Synonym Gene Names
AQP-9??[Similar Products]
UniProt Entry Name
AQP9_MOUSE
NCBI Summary for Aqp9
This gene encodes a member of the aquaglyceroporin subfamily of aquaporins. This protein transports water, glycerol, urea, purines and pyrimidines and plays a role in glycerol metabolism and osteoclast differentiation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012]
UniProt Comments for Aqp9
AQP9: Forms a channel with a broad specificity. Mediates passage of a wide variety of non-charged solutes including carbamides, polyols, purines, and pyrimidines in a phloretin- and mercury-sensitive manner, whereas amino acids, cyclic sugars, Na(+), K(+), Cl(-), and deprotonated monocarboxylates are excluded. Also permeable to urea and glycerol. Belongs to the MIP/aquaporin (TC 1.A.8) family.
Protein type: Transporter; Transporter, aquaporin family; Membrane protein, integral; Membrane protein, multi-pass; Channel, misc.
Cellular Component: basolateral plasma membrane; integral to membrane; integral to plasma membrane; intracellular membrane-bound organelle; membrane
Molecular Function: glycerol channel activity; purine transmembrane transporter activity; pyrimidine transmembrane transporter activity; transporter activity; urea channel activity; urea transmembrane transporter activity; water channel activity
Biological Process: amine transport; canalicular bile acid transport; cellular response to stress; cellular water homeostasis; polyol transport; purine transport; pyrimidine transport; response to mercury ion; response to organic substance; transport; water transport
Research Articles on Aqp9
1. Results suggest implication of AQP9 in liver steatosis. The reduction of hepatocyte AQP9 and, consequently, glycerol permeability might be a defensive mechanism to counteract further fat infiltration in liver parenchyma.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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