Product Name
SGLT-2, Peptide
Full Product Name
SGLT-2 Blocking Peptide
Product Gene Name
SGLT-2 peptide
[Similar Products]
SGLT-2 peptide (MBS843923) is used for blocking the activity of SGLT-2 antibody (MBS841348)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q923I7
Form/Format
50 ug (0.2 mg/ml) in phosphate buffered saline (PBS), pH 7.2, containing 0.1% BSA and 0.02% thimerosal.
Appearance: Colorless liquid
Concentration
0.2 mg/ml (lot specific)
Handling
The peptide solution should be gently mixed before use.
Preparation and Storage
At -20 degree C
Shelf Life: 12 months
Other Notes
Small volumes of SGLT-2 peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for SGLT-2 peptide
Western Blot (WB)
Application Notes for SGLT-2 peptide
The peptide is used for blocking the antibody activity of active SGLT-2. It usually blocks the antibody activity completely in Western blot analysis by incubating the peptide with equal volume of antibody for 30 minutes at 37 degree C
Testing Data of SGLT-2 peptide
NCBI/Uniprot data below describe general gene information for SGLT-2. It may not necessarily be applicable to this product.
NCBI Accession #
NP_573517.1
[Other Products]
NCBI GenBank Nucleotide #
NM_133254.3
[Other Products]
UniProt Primary Accession #
Q923I7
[Other Products]
UniProt Related Accession #
Q923I7[Other Products]
Molecular Weight
73,008 Da
NCBI Official Full Name
sodium/glucose cotransporter 2
NCBI Official Synonym Full Names
solute carrier family 5 (sodium/glucose cotransporter), member 2
NCBI Official Symbol
Slc5a2??[Similar Products]
NCBI Official Synonym Symbols
Sglt2
??[Similar Products]
NCBI Protein Information
sodium/glucose cotransporter 2
UniProt Protein Name
Sodium/glucose cotransporter 2
UniProt Synonym Protein Names
Low affinity sodium-glucose cotransporter; Solute carrier family 5 member 2
UniProt Gene Name
Slc5a2??[Similar Products]
UniProt Synonym Gene Names
Sglt2; Na(+)/glucose cotransporter 2??[Similar Products]
UniProt Entry Name
SC5A2_MOUSE
UniProt Comments for SGLT-2
SLC5A2: Sodium-dependent glucose transporter. Has a Na(+) to glucose coupling ratio of 1:1. Defects in SLC5A2 are the cause of renal glucosuria (GLYS1). GLYS1 is an autosomal recessive disorder characterized by a normal fasting serum glucose concentration and persistent isolated glucosuria, with a normal glucose tolerance test. Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
Protein type: Transporter, SLC family; Membrane protein, integral; Membrane protein, multi-pass; Transporter
Cellular Component: membrane; brush border membrane; integral to membrane
Molecular Function: protein binding; glucose:sodium symporter activity; transporter activity; symporter activity
Biological Process: transport; sodium ion transport; carbohydrate transport; ion transport; glucose transport; transmembrane transport
Research Articles on SGLT-2
1. DNA sequencing of SGLT2 in SAMP10/TaSlc mice revealed a single nucleotide deletion of guanine at 1236, which resulted in a frameshift mutation that produced a truncated protein.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
