Product Name
alpha sarcoglycan (Alpha-SG), Monoclonal Antibody
Full Product Name
alpha sarcoglycan
Product Synonym Names
Alpha-sarcoglycan; 50 kDa dystrophin-associated glycoprotein; Adhalin; Dystroglycan-2
Product Gene Name
anti-Alpha-SG antibody
[Similar Products]
Product Synonym Gene Name
50DAG; SGCA[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q16586
Species Reactivity
Human, Mouse, Rat
Purity/Purification
ProA affinity purified
Immunogen
Recombinant Protein
Storage Buffer
1*TBS (pH7.4), 1% BSA, 40% Glycerol.
Preservative
0.107% Sodium Azide.
Preparation and Storage
Aliquot and store at-20 degree C. Avoid repeated freeze/thaw cycles.
Other Notes
Small volumes of anti-Alpha-SG antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-Alpha-SG antibody
Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC)
NCBI/Uniprot data below describe general gene information for Alpha-SG. It may not necessarily be applicable to this product.
NCBI Accession #
NP_000014.1
[Other Products]
NCBI GenBank Nucleotide #
NM_000023.3
[Other Products]
UniProt Primary Accession #
Q16586
[Other Products]
UniProt Secondary Accession #
Q13710; Q13712; A6NEB8; A8K3K7[Other Products]
UniProt Related Accession #
Q16586[Other Products]
Molecular Weight
29,354 Da
NCBI Official Full Name
alpha-sarcoglycan isoform 1
NCBI Official Synonym Full Names
sarcoglycan alpha
NCBI Official Symbol
SGCA??[Similar Products]
NCBI Official Synonym Symbols
ADL; DAG2; 50DAG; DMDA2; LGMD2D; SCARMD1; adhalin
??[Similar Products]
NCBI Protein Information
alpha-sarcoglycan
UniProt Protein Name
Alpha-sarcoglycan
UniProt Synonym Protein Names
50 kDa dystrophin-associated glycoprotein; 50DAG; Adhalin; Dystroglycan-2
UniProt Gene Name
SGCA??[Similar Products]
UniProt Synonym Gene Names
ADL; DAG2; Alpha-SG; 50DAG??[Similar Products]
NCBI Summary for Alpha-SG
This gene encodes a component of the dystrophin-glycoprotein complex (DGC), which is critical to the stability of muscle fiber membranes and to the linking of the actin cytoskeleton to the extracellular matrix. Its expression is thought to be restricted to striated muscle. Mutations in this gene result in type 2D autosomal recessive limb-girdle muscular dystrophy. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]
UniProt Comments for Alpha-SG
Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
Research Articles on Alpha-SG
1. Pathogenic mutations were found in SGCA from Egyptian families with limb-girdle muscular dystrophy.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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