Anti-C/EBP Epsilon / CEBPE Antibody (aa191-240) IHC-plus; CEBPE; CRP1; C/EBP epsilon; C/EBP-epsilon; Human C/EBP Epsilon; CEBPE

For Research Use Only. Not for use in diagnostic procedures.

Polyclonal

IgG

Rabbit

CEBPE Antibody detects endogenous levels of total CEBPE protein.

Immunoaffinity Purified

PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol

1 mg/ml (lot specific)

Store at -20 degree C for up to one year.

Small volumes of anti-CEBPE antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)

ELISA (1:10000), IHC-P (10 ug/ml), WB (1:500 - 1:1000)

Anti-C/EBP Epsilon / CEBPE antibody IHC staining of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.

Western blot of extracts from NIH-3T3 cells, using CEBPE Antibody. The lane on the right is treated with the synthesized peptide.

30,603 Da

CCAAT/enhancer binding protein (C/EBP), epsilon

CCAAT/enhancer-binding protein epsilon; c/EBP epsilon

CCAAT/enhancer-binding protein epsilon

C/EBP epsilon??[Similar Products]

CEBPE_HUMAN

The protein encoded by this gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related protein CEBP-delta. The encoded protein may be essential for terminal differentiation and functional maturation of committed granulocyte progenitor cells. Mutations in this gene have been associated with Specific Granule Deficiency, a rare congenital disorder. Multiple variants of this gene have been described, but the full-length nature of only one has been determined. [provided by RefSeq, Jul 2008]

C/EBP-epsilon: C/EBP are DNA-binding proteins that recognize two different motifs: the CCAAT homology common to many promoters and the enhanced core homology common to many enhancers. Belongs to the bZIP family. C/EBP subfamily.

Protein type: Motility/polarity/chemotaxis; Transcription factor; DNA-binding

Chromosomal Location of Human Ortholog: 14q11.2

Cellular Component: nucleoplasm

Molecular Function: protein homodimerization activity; protein heterodimerization activity

Biological Process: macrophage differentiation; transcription, DNA-dependent; cytokine biosynthetic process; defense response to bacterium; defense response; positive regulation of transcription from RNA polymerase II promoter; phagocytosis

Disease: Specific Granule Deficiency

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