Full Product Name
SGLT2 Antibody FITC-Conjugated
Product Synonym Names
Low affinity sodium glucose cotransporter; Na(+) glucose cotransporter 2; SGLT 2; SLC5A2; Sodium glucose cotransporter 2; Solute carrier family 5 (sodium glucose cotransporter) member 2 antibodySolute carrier family 5 member 2 antibody
Product Gene Name
anti-SGLT2 antibody
[Similar Products]
Matching Pairs
Antibody: SGLT2 (MBS544868)
Positive Control: SGLT2 (MBS543251)
Antibody/Peptide Pairs
SGLT2 peptide (MBS544463) is used for blocking the activity of SGLT2 antibody (MBS544868)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P31639
Species Reactivity
Human, Monkey, Mouse
Form/Format
FITC-Conjugated
Concentration
0.65 ug/ul in antibody stabilization buffer (lot specific)
Immunogen
Synthetic peptide taken within amino acid region 580-630 on human SGLT2 protein.
Molecular Function
Low-affinity glucose: sodium symporter activity
Structure
Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
Subcellular Location
Membrane; Multi-pass membrane protein
Preparation and Storage
-20? degree C for long term storage
Other Notes
Small volumes of anti-SGLT2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-SGLT2 antibody
FITC-Conjugated Sodium/glucose cotransporter 2 Antibody
Sodium-dependent glucose transporter. Has a Na+ to glucose coupling ratio of 1:1.
Efficient substrate transport in mammalian kidney is provided by the concerted action of a low affinity high capacity and a high affinity low capacity Na+/glucose cotransporter arranged in series along kidney proximal tubules.
Applications Tested/Suitable for anti-SGLT2 antibody
Confocal Microscopy (CM), ELISA (EIA), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB)
Application Notes for anti-SGLT2 antibody
Confocal Microscopy||1:50
Dot Blot: 1:10,000
ELISA: 1:10,000
Immunocytochemistry: 1:50
Immunofluorescence: 1:50
Immunohistochemistry: 1:50
Immunoprecipitation: 1:150
Western Blot: 1:500
NCBI/Uniprot data below describe general gene information for SGLT2. It may not necessarily be applicable to this product.
NCBI Accession #
NP_003032
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NCBI GenBank Nucleotide #
NM_003041.3
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UniProt Primary Accession #
P31639
[Other Products]
UniProt Secondary Accession #
A2RRD2[Other Products]
Molecular Weight
49,357 Da
NCBI Official Full Name
sodium/glucose cotransporter 2
UniProt Protein Name
Sodium/glucose cotransporter 2
UniProt Synonym Protein Names
Low affinity sodium-glucose cotransporter; Solute carrier family 5 member 2
UniProt Gene Name
SLC5A2??[Similar Products]
UniProt Synonym Gene Names
SGLT2; Na(+)/glucose cotransporter 2??[Similar Products]
UniProt Entry Name
SC5A2_HUMAN
UniProt Comments for SGLT2
SLC5A2: Sodium-dependent glucose transporter. Has a Na(+) to glucose coupling ratio of 1:1. Defects in SLC5A2 are the cause of renal glucosuria (GLYS1). GLYS1 is an autosomal recessive disorder characterized by a normal fasting serum glucose concentration and persistent isolated glucosuria, with a normal glucose tolerance test. Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
Protein type: Transporter; Membrane protein, multi-pass; Transporter, SLC family; Membrane protein, integral
Chromosomal Location of Human Ortholog: 16p11.2
Cellular Component: brush border membrane; integral to membrane; integral to plasma membrane; plasma membrane
Molecular Function: glucose:sodium symporter activity; low-affinity glucose:sodium symporter activity
Biological Process: carbohydrate metabolic process; sodium ion transport; transport
Disease: Renal Glucosuria
Precautions
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Disclaimer
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