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SGLT2, Polyclonal Antibody

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產(chǎn)品名稱(chēng): SGLT2, Polyclonal Antibody
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SGLT2, Polyclonal Antibody


SGLT2, Polyclonal Antibody  的詳細(xì)介紹
Product Name

SGLT2, Polyclonal Antibody

Popular Item
Full Product Name

SGLT2 antibody

Product Synonym Names
Polyclonal SGLT2 antibody, anti-SGLT2 antibody, SGLT 2 antibody, SGLT2, SGLT-2 antibody, SGLT 2, SLC5A2 antibody, SGLT 2 antibody, SGLT-2, antibody, SLC5A 2 antibody, SGLT-2 antibody
Product Gene Name

anti-SGLT2 antibody

[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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OMIM
182381
3D Structure
ModBase 3D Structure for P31639
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human,Rat, Mouse
Purity/Purification
SGLT2 antibody was purified by affinity chromatography
Form/Format
Liquid in PBS containing 30% glycerol, 0.5% BSA, 5mM EDTA and 0.03% Proclin
Concentration
0.5 mg/ml (lot specific)
Assay Information
Biological Significance
Immunogen
Synthetic peptide near the N-terminus of mouse SGLT-2
Preparation and Storage
Shipping: Blue Ice.
Upon receipt store at -20°C short term. For long term storage, aliquot and store at -70°C. Avoid repeated freeze/thaw cycles.
Other Notes
Small volumes of anti-SGLT2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for
anti-SGLT2 antibody
Rabbit polyclonal SGLT2 antibody
Product Categories/Family for anti-SGLT2 antibody
Nutrition & Metabolism; Purified Polyclonal Antibodies
Applications Tested/Suitable for anti-SGLT2 antibody
Suitable for use in Western Blot (WB).
Application Notes for anti-SGLT2 antibody
Western Blot: 0.5-4 ug/ml, however the optimal concentrations should be determined individually

Western Blot (WB) of anti-SGLT2 antibody
Western blot analysis of SGLT-2 in lysate from Jurkat cells (Lane 1), mouse small intestine (Lane 2) and rat kidey (Lane 3).
anti-SGLT2 antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for SGLT2. It may not necessarily be applicable to this product.
NCBI GI #
4507033
NCBI GeneID
6524
NCBI Accession #
NP_003032.1 [Other Products]
NCBI GenBank Nucleotide #
NM_003041.3 [Other Products]
UniProt Primary Accession #
P31639 [Other Products]
UniProt Secondary Accession #
A2RRD2[Other Products]
UniProt Related Accession #
P31639[Other Products]
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NCBI Official Full Name
sodium/glucose cotransporter 2
NCBI Official Synonym Full Names
solute carrier family 5 (sodium/glucose cotransporter), member 2
NCBI Official Symbol
SLC5A2??[Similar Products]
NCBI Official Synonym Symbols
SGLT2
??[Similar Products]
NCBI Protein Information
sodium/glucose cotransporter 2
UniProt Protein Name
Sodium/glucose cotransporter 2
UniProt Synonym Protein Names
Low affinity sodium-glucose cotransporter; Solute carrier family 5 member 2
UniProt Gene Name
SLC5A2??[Similar Products]
UniProt Synonym Gene Names
SGLT2; Na(+)/glucose cotransporter 2??[Similar Products]
UniProt Entry Name
SC5A2_HUMAN
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NCBI Summary for SGLT2
This gene encodes a member of the sodium glucose cotransporter family which are sodium-dependent glucose transport proteins. The encoded protein is the major cotransporter involved in glucose reabsorption in the kidney. Mutations in this gene are associated with renal glucosuria. Two transcript variants, one protein-coding and one not, have been found for this gene. [provided by RefSeq, Feb 2015]
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UniProt Comments for SGLT2
SLC5A2: Sodium-dependent glucose transporter. Has a Na(+) to glucose coupling ratio of 1:1. Defects in SLC5A2 are the cause of renal glucosuria (GLYS1). GLYS1 is an autosomal recessive disorder characterized by a normal fasting serum glucose concentration and persistent isolated glucosuria, with a normal glucose tolerance test. Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.

Protein type: Transporter, SLC family; Membrane protein, integral; Transporter; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 16p11.2

Cellular Component: plasma membrane; integral to membrane

Molecular Function: low-affinity glucose:sodium symporter activity

Biological Process: transport; carbohydrate metabolic process; sodium ion transport; glucose transport; transmembrane transport

Disease: Renal Glucosuria
Research Articles on SGLT2
1. Sodium glucose cotransporter 2 inhibitor empagliflozin is not associated with prolonged QT interval.
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Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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