Product Name
SLC5A2, cDNA Clone
Full Product Name
SLC5A2 cDNA Clone
Product Gene Name
SLC5A2 cdna clone
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
ATGGAGGAGC ACACAGAGGC AGGCTCGGCA CCAGAGATGG GGGCCCAGAA GGCCCTGATT GACAATCCTG CTGACATCCT AGTCATTGCT GCATATTTCC TGCTGGTCAT TGGCGTTGGC TTGTGGTCCA TGTGCAGAAC CAACAGAGGC ACTGTGGGCG GCTACTTCCT GGCAGGACGC AGCATGGTGT GGTGGCCGGT TGGGGCCTCT CTCTTCGCCA GCAACATCGG CAGTGGCCAC TTTGTGGGCC TGGCAGGGAC TGGCGCTGCA AGTGGCTTGG CTGTTGCTGG ATTCGAGTGG AATGCGCTCT TCGTGGTGCT GCTACTGGGC TGGCTGTTTG CACCCGTGTA CCTGACAGCG GGGGTCATCA CGATGCCACA GTACCTGCGC AAGCGCTTCG GCGGCCGCCG CATCCGCCTC TACCTGTCTG TGCTCTCCCT TTTCCTGTAC ATCTTCACCA AGATCTCAGT GGACATGTTC TCCGGAGCTG TATTCATCCA GCAGGCTCTG GGCTGGAACA TCTATGCCTC CGTCATCGCG CTTCTGGGCA TCACCATGAT TTACACGGTG ACAGGAGGGC TGGCCGCGCT GATGTACACG GACACGGTAC AGACCTTCGT CATTCTGGGG GGCGCCTGCA TCCTCATGGG TTACGCCTTC CACGAGGTGG GCGGGTATTC GGGTCTCTTC GACAAATACC TGGGAGCAGC GACTTCGCTG ACGGTGTCCG AGGATCCAGC CGTGGGAAAC ATCTCCAGCT TCTGCTATCG ACCCCGGCCC GACTCCTACC ACCTGCTCCG GCACCCCGTG ACCGGGGATC TGCCGTGGCC CGCGCTGCTC CTCGGACTCA CAATCGTCTC GGGCTGGTAC TGGTGCAGCG ACCAGGTCAT CGTGCAGCGC TGCCTGGCCG GGAAGAGCCT GACCCACATC AAGGCGGGCT GCATCCTGTG TGGGTACCTG AAGCTGACGC CCATGTTTCT CATGGTCATG CCAGGCATGA TCAGCCGCAT TCTGTACCCA GACGAGGTGG CGTGCGTGGT GCCTGAGGTG TGCAGGCGCG TGTGCGGCAC GGAGGTGGGC TGCTCCAACA TCGCCTACCC GCGGCTCGTC GTGAAGCTCA TGCCCAACGG GCGCCTTCTG GGGACTCATC GGGGGCCTGC TGATGGGCCT GGCACGCCTG ATTCCCGAGT TCTCCTTCGG CTCGGGCAGC TGTGTGCAGC CCTCGGCGTG CCCAGCTTTC CTCTGCGGCG TGCACTACCT CTACTTCGCC ATTGTGCTGT TCTTCTGCTC TGGCCTCCTC ACCCTCACGG TCTCCCTGTG CACCGCGCCC ATCCCCAGAA AGCACCTCCA CCGCCTGGTC TTCAGTCTCC GGCATAG
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of SLC5A2 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for SLC5A2. It may not necessarily be applicable to this product.
NCBI Accession #
BC131542
[Other Products]
UniProt Secondary Accession #
A2RRD2[Other Products]
UniProt Related Accession #
P31639[Other Products]
Molecular Weight
49,357 Da
NCBI Official Full Name
Homo sapiens solute carrier family 5 (sodium/glucose cotransporter), member 2, mRNA
NCBI Official Synonym Full Names
solute carrier family 5 member 2
NCBI Official Symbol
SLC5A2??[Similar Products]
NCBI Official Synonym Symbols
SGLT2
??[Similar Products]
NCBI Protein Information
sodium/glucose cotransporter 2
UniProt Protein Name
Sodium/glucose cotransporter 2
UniProt Synonym Protein Names
Low affinity sodium-glucose cotransporter; Solute carrier family 5 member 2
Protein Family
Sodium/glucose cotransporter
UniProt Gene Name
SLC5A2??[Similar Products]
UniProt Synonym Gene Names
SGLT2; Na(+)/glucose cotransporter 2??[Similar Products]
UniProt Entry Name
SC5A2_HUMAN
NCBI Summary for SLC5A2
This gene encodes a member of the sodium glucose cotransporter family which are sodium-dependent glucose transport proteins. The encoded protein is the major cotransporter involved in glucose reabsorption in the kidney. Mutations in this gene are associated with renal glucosuria. Two transcript variants, one protein-coding and one not, have been found for this gene. [provided by RefSeq, Feb 2015]
UniProt Comments for SLC5A2
SLC5A2: Sodium-dependent glucose transporter. Has a Na(+) to glucose coupling ratio of 1:1. Defects in SLC5A2 are the cause of renal glucosuria (GLYS1). GLYS1 is an autosomal recessive disorder characterized by a normal fasting serum glucose concentration and persistent isolated glucosuria, with a normal glucose tolerance test. Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
Protein type: Transporter; Membrane protein, multi-pass; Membrane protein, integral; Transporter, SLC family
Chromosomal Location of Human Ortholog: 16p11.2
Cellular Component: integral to membrane; integral to plasma membrane; plasma membrane
Molecular Function: glucose:sodium symporter activity; low-affinity glucose:sodium symporter activity
Biological Process: carbohydrate metabolic process; transport
Disease: Renal Glucosuria
Research Articles on SLC5A2
1. Mutations in the SLC5A2 gene did not find any evidence that chronic loss of glucose in the urine would protect from deterioration of the glucose tolerance over time.
Precautions
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Disclaimer
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