Full Product Name
Anti-FTCD Antibody
Product Synonym Names
Formimidoyltransferase-cyclodeaminase; Formiminotransferase-cyclodeaminase; FTCD; LCHC1
Product Gene Name
anti-FTCD antibody
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Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for O95954
Species Reactivity
Human, Mouse, Rat
Specificity
Recognizes endogenous levels of FTCD protein.
Purity/Purification
Purified by immunogen affinity chromatography
Form/Format
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Immunogen
Recombinant full length protein of human FTCD
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
Other Notes
Small volumes of anti-FTCD antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-FTCD antibody
Rabbit polyclonal antibody to FTCD
Applications Tested/Suitable for anti-FTCD antibody
Western Blot (WB)
Application Notes for anti-FTCD antibody
WB: 1/500 - 1/2000
Western Blot (WB) of anti-FTCD antibody
Western blot analysis of FTCD expression in LO2 (A), mouse liver (B), rat kidney (C) whole cell lysates.
NCBI/Uniprot data below describe general gene information for FTCD. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001307341.1
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NCBI GenBank Nucleotide #
NM_001320412.1
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UniProt Primary Accession #
O95954
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UniProt Secondary Accession #
Q86V03; Q9HCT4; Q9HCT5; Q9HCT6; Q9UHJ2; B9EGD0[Other Products]
UniProt Related Accession #
O95954[Other Products]
Molecular Weight
16,503 Da
NCBI Official Full Name
formimidoyltransferase-cyclodeaminase isoform C
NCBI Official Synonym Full Names
formimidoyltransferase cyclodeaminase
NCBI Official Symbol
FTCD??[Similar Products]
NCBI Official Synonym Symbols
LCHC1
??[Similar Products]
NCBI Protein Information
formimidoyltransferase-cyclodeaminase
UniProt Protein Name
Formimidoyltransferase-cyclodeaminase
UniProt Synonym Protein Names
Formiminotransferase-cyclodeaminase; FTCD; LCHC1Including the following 2 domains:Glutamate formimidoyltransferase (EC:2.1.2.5)Alternative name(s):Glutamate formiminotransferase; Glutamate formyltransferase
Protein Family
Formimidoyltransferase-cyclodeaminase
UniProt Gene Name
FTCD??[Similar Products]
UniProt Synonym Gene Names
FTCD??[Similar Products]
NCBI Summary for FTCD
The protein encoded by this gene is a bifunctional enzyme that channels 1-carbon units from formiminoglutamate, a metabolite of the histidine degradation pathway, to the folate pool. Mutations in this gene are associated with glutamate formiminotransferase deficiency. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Dec 2009]
UniProt Comments for FTCD
Folate-dependent enzyme, that displays both transferase and deaminase activity. Serves to channel one-carbon units from formiminoglutamate to the folate pool.Binds and promotes bundling of vimentin filaments originating from the Golgi.
Research Articles on FTCD
1. FTCD is a positive regulator of the hypoxia-HIF signaling pathway and has an important role in cell proliferation, metabolism and migration in HepG2 cells
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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