Full Product Name
FBXO9 (F-box Only Protein 9, FBX9, DJ341E18.2, DKFZP434C0118, KIAA0936, NY-REN-57, VCIA1)
Product Synonym Names
Anti -FBXO9 (F-box Only Protein 9, FBX9, DJ341E18.2, DKFZP434C0118, KIAA0936, NY-REN-57, VCIA1)
Product Gene Name
anti-FBXO9 antibody
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Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Chromosome Location
Chromosome: 6; NC_000006.11 (52929796..52965671). Location: 6p12.3-p11.2
3D Structure
ModBase 3D Structure for Q4W8W0
Species Reactivity
Bovine, Chicken, Frog, Human, Mouse, Rat0
Specificity
Recognizes Human F-box Only Protein 9 (FBXO9). Species Crossreactivity: Bovine, Chimpanzee, Chicken, Dog, Frog, Human, Mouse, Rat, Zebrafish.
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.01% sodium azide.
Immunogen
Synthetic peptide, KLH-conjugated. Epitope: Amino acids 431-447 of human FBOX9 protein.
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Other Notes
Small volumes of anti-FBXO9 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for anti-FBXO9 antibody
Antibodies; Abs to Ubiquitin Ligases
Applications Tested/Suitable for anti-FBXO9 antibody
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes for anti-FBXO9 antibody
Suitable for use in ELISA, Immunofluorescence, Western Blot and Immunohistochemistry.
Dilution: Immunohistochemistry: 5ug/ml
Western Blot: 1:500-1:2000
ELISA: 1:5000-1:25,000
NCBI/Uniprot data below describe general gene information for FBXO9. It may not necessarily be applicable to this product.
NCBI Accession #
NP_258442.2
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NCBI GenBank Nucleotide #
NM_033481.3
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UniProt Primary Accession #
Q4W8W0
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UniProt Related Accession #
Q4W8W0; Q59EH8; Q9UK97[Other Products]
Molecular Weight
48,864 Da[Similar Products]
NCBI Official Full Name
F-box only protein 9 isoform 3
NCBI Official Synonym Full Names
F-box protein 9
NCBI Official Symbol
FBXO9??[Similar Products]
NCBI Official Synonym Symbols
FBX9; VCIA1; KIAA0936; NY-REN-57; dJ341E18.2; DKFZp434C0118
??[Similar Products]
NCBI Protein Information
F-box only protein 9; F-box protein Fbx9; OTTHUMP00000016628; OTTHUMP00000016629; OTTHUMP00000214588; cross-immune reaction antigen 1; renal carcinoma antigen NY-REN-57
UniProt Protein Name
NY-REN-57 antigen
Protein Family
F-box only protein
UniProt Entry Name
Q4W8W0_HUMAN
NCBI Summary for FBXO9
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Alternative splicing of this gene generates at least 3 transcript variants diverging at the 5' terminus. [provided by RefSeq]
UniProt Comments for FBXO9
FBXO9 iso4: Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Ubiquitin conjugating system; Ligase
Chromosomal Location of Human Ortholog: 6p12.3-p11.2
Cellular Component: cytoplasm; SCF ubiquitin ligase complex; ubiquitin ligase complex
Molecular Function: protein binding; ubiquitin-protein ligase activity
Biological Process: fat cell differentiation; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; protein ubiquitination; innate immune response; regulation of TOR signaling pathway
Research Articles on FBXO9
1. ICK and FBX9 are divergently transcribed from a bidirectional promoter that is GC-rich and contains a CpG island.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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