Full Product Name
APRT Antibody
Product Gene Name
anti-APRT antibody
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Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P07741
Other Notes
Small volumes of anti-APRT antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for APRT. It may not necessarily be applicable to this product.
NCBI Accession #
NP_000476.1
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NCBI GenBank Nucleotide #
NM_000485.2
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UniProt Primary Accession #
P07741
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UniProt Secondary Accession #
Q3KP55; Q68DF9; G5E9J2[Other Products]
UniProt Related Accession #
P07741[Other Products]
Molecular Weight
14,557 Da
NCBI Official Full Name
adenine phosphoribosyltransferase isoform a
NCBI Official Synonym Full Names
adenine phosphoribosyltransferase
NCBI Official Symbol
APRT??[Similar Products]
NCBI Official Synonym Symbols
AMP; APRTD
??[Similar Products]
NCBI Protein Information
adenine phosphoribosyltransferase
UniProt Protein Name
Adenine phosphoribosyltransferase
Protein Family
Probable adenine phosphoribosyltransferase
UniProt Gene Name
APRT??[Similar Products]
UniProt Synonym Gene Names
APRT??[Similar Products]
NCBI Summary for APRT
Adenine phosphoribosyltransferase belongs to the purine/pyrimidine phosphoribosyltransferase family. A conserved feature of this gene is the distribution of CpG dinucleotides. This enzyme catalyzes the formation of AMP and inorganic pyrophosphate from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP). It also produces adenine as a by-product of the polyamine biosynthesis pathway. A homozygous deficiency in this enzyme causes 2,8-dihydroxyadenine urolithiasis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
UniProt Comments for APRT
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
Research Articles on APRT
1. A long TA repeat in the promoter region of IL28B was associated with spontaneous HCV clearance.
Precautions
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Disclaimer
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