For Research Use Only. Not for use in diagnostic procedures.

Polyclonal

Rabbit

Affinity Purified

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Small volumes of anti-SLC26A1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

This is a rabbit polyclonal antibody against SLC26A1. It was validated on Western Blot and immunohistochemistry

Target Description: SLC26A1 is a member of sulfate/anion transporter family. Family members are well conserved in their protein (aa length among species) structures, but have markedly different tissue expression patterns. Its gene is primarily expressed in the liver, pancreas, and brain.This gene is a member of a family of sulfate/anion transporter genes. Family members are well conserved in their genomic (number and size of exons) and protein (aa length among species) structures, but have markedly different tissue expression patterns. This gene is primarily expressed in the liver, pancreas, and brain. Three splice variants that encode different isoforms have been identified.

Polyclonal; Membrane Protein; Immunohistochemistry;

Immunohistochemistry (IHC), Western Blot (WB)

Human Skin

WB Suggested Anti-SLC26A1 Antibody Titration: 0.2-1 ug/ml
Positive Control: HepG2 cell lysate

77kDa

solute carrier family 26 member 1

sulfate anion transporter 1

Sulfate anion transporter 1

SAT1; SAT-1??[Similar Products]

S26A1_HUMAN

This gene is a member of a family of sulfate/anion transporter genes. Family members are well conserved in their genomic (number and size of exons) and protein (aa length among species) structures, but have markedly different tissue expression patterns. This gene is primarily expressed in the liver, pancreas, and brain. Three splice variants that encode different isoforms have been identified. [provided by RefSeq, Jul 2008]

SLC26A1: High affinity uptake of sulfate. Accepts oxalate, but not succinate as a cosubstrate. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Transporter, SLC family; Membrane protein, multi-pass; Membrane protein, integral; Transporter

Chromosomal Location of Human Ortholog: 4p16.3

Cellular Component: integral to membrane; integral to plasma membrane; plasma membrane

Molecular Function: anion:anion antiporter activity; bicarbonate transmembrane transporter activity; chloride channel activity; chloride transmembrane transporter activity; oxalate transmembrane transporter activity; secondary active sulfate transmembrane transporter activity; sulfate transmembrane transporter activity

Biological Process: 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process; 3'-phosphoadenosine 5'-phosphosulfate metabolic process; bicarbonate transport; carbohydrate metabolic process; chloride transport; glycosaminoglycan metabolic process; ion transport; oxalate transport; regulation of intracellular pH; regulation of membrane potential; sulfate transport; transmembrane transport; xenobiotic metabolic process

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