Product Name
72 kDa type IV collagenase (Mmp2), Polyclonal Antibody
Full Product Name
Rabbit anti-rat 72 kDa type IV collagenase polyclonal Antibody, HRP conjugated
Product Synonym Names
72 kDa gelatinase; Gelatinase A; Matrix metalloproteinase-2; MMP-2; Mmp2
Product Gene Name
anti-Mmp2 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P33436
Purity/Purification
Caprylic Acid Ammonium Sulfate Precipitation Purified
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Immunogen
Recombinant rat 72 kDa type IV collagenase protein(110-662AA)
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of anti-Mmp2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-Mmp2 antibody
Ubiquitinous metalloproteinase that is involved in diverse functions such as remodeling of the vasculature, angiogenesis, tissue repair, tumor invasion, inflammation, and atherosclerotic plaque rupture. As well as degrading extracellular matrix proteins, can also act on several nonmatrix proteins such as big endothelial 1 and beta-type CGRP promoting vasoconstriction. Also cleaves KISS at a Gly-|-Leu bond. Appears to have a role in myocardial cell death pathways. Contributes to myocardial oxidative stress by regulating the activity of GSK3beta. Cleaves GSK3beta in vitro. Involved in the formation of the fibrovascular tissues (By similarity).
Applications Tested/Suitable for anti-Mmp2 antibody
ELISA (EIA)
NCBI/Uniprot data below describe general gene information for Mmp2. It may not necessarily be applicable to this product.
NCBI Accession #
NP_112316.2
[Other Products]
NCBI GenBank Nucleotide #
NM_031054.2
[Other Products]
UniProt Primary Accession #
P33436
[Other Products]
UniProt Secondary Accession #
P97581; Q6GMM9[Other Products]
UniProt Related Accession #
P33436[Other Products]
Molecular Weight
74,149 Da[Similar Products]
NCBI Official Full Name
72 kDa type IV collagenase
NCBI Official Synonym Full Names
matrix metallopeptidase 2
NCBI Official Symbol
Mmp2??[Similar Products]
NCBI Protein Information
72 kDa type IV collagenase
UniProt Protein Name
72 kDa type IV collagenase
UniProt Synonym Protein Names
72 kDa gelatinase; Gelatinase A; Matrix metalloproteinase-2; MMP-2
Protein Family
72 kDa type IV collagenase
UniProt Gene Name
Mmp2??[Similar Products]
UniProt Synonym Gene Names
MMP-2??[Similar Products]
UniProt Entry Name
MMP2_RAT
NCBI Summary for Mmp2
plays important roles in wound healing, angiogenesis, platelet aggregation, and tumor metastasis; mediates the response of the intrinsic glomerular mesangial cell to inflammatory stimuli [RGD, Feb 2006]
UniProt Comments for Mmp2
Ubiquitinous metalloproteinase that is involved in diverse functions such as remodeling of the vasculature, angiogenesis, tissue repair, tumor invasion, inflammation, and atherosclerotic plaque rupture. As well as degrading extracellular matrix proteins, can also act on several nonmatrix proteins such as big endothelial 1 and beta-type CGRP promoting vasoconstriction. Also cleaves KISS at a Gly-|-Leu bond. Appears to have a role in myocardial cell death pathways. Contributes to myocardial oxidative stress by regulating the activity of GSK3beta. Cleaves GSK3beta in vitro. Involved in the formation of the fibrovascular tissues ().
Research Articles on Mmp2
1. autophagy could regulate the EPCs migration through mTOR-P70 S6K pathway, and MMP2, MMP9 and uPA may also involve in the regulation mechanism
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
